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挪威结痂性疥疮:一例罕见病例报告。

Norwegian crusted scabies: an unusual case presentation.

作者信息

Maghrabi Michael M, Lum Shireen, Joba Ameha T, Meier Molly J, Holmbeck Ryan J, Kennedy Kate

机构信息

Director of Podiatric Medicine and Surgery Residency Program, Presence Health, Saints Mary and Elizabeth Medical Center, Chicago, IL.

Attending, Presence Health, Saints Mary and Elizabeth Medical Center, Chicago, IL.

出版信息

J Foot Ankle Surg. 2014 Jan-Feb;53(1):62-6. doi: 10.1053/j.jfas.2013.09.002.

Abstract

Scabies is a contagious condition that is transmitted through direct contact with an infected person and has been frequently associated with institutional and healthcare-facility outbreaks. The subtype Norwegian crusted scabies can masquerade as other dermatologic diseases owing to the heavy plaque formation. Successful treatment has been documented in published reports, including oral ivermectin and topical permethrin. Few case studies documenting the treatment of Norwegian crusted scabies have reported the use of surgical debridement as an aid to topical and/or oral treatment when severe plaque formation has been noted. A nursing home patient was admitted to the hospital for severe plaque formation of both feet. A superficial biopsy was negative for both fungus and scabies because of the severity of the plaque formation on both feet. The patient underwent a surgical, diagnostic biopsy of both feet, leading to the diagnosis of Norwegian crusted scabies. A second surgical debridement was then performed to remove the extensive plaque formation and aid the oral ivermectin and topical permethrin treatment. The patient subsequently made a full recovery and was discharged back to the nursing home. At 2 and 6 months after treatment, the patient remained free of scabies infestation, and the surgical wound had healed uneventfully. The present case presentation has demonstrated that surgical debridement can be complementary to the standard topical and oral medications in the treatment of those with Norwegian crusted scabies infestation.

摘要

疥疮是一种通过与感染者直接接触传播的传染性疾病,经常与机构和医疗保健机构的疫情爆发有关。挪威结痂性疥疮亚型由于形成大量斑块,可能会伪装成其他皮肤病。已发表的报告记录了成功的治疗方法,包括口服伊维菌素和外用氯菊酯。很少有记录挪威结痂性疥疮治疗的案例研究报告,在发现严重斑块形成时,使用手术清创作为局部和/或口服治疗的辅助手段。一名疗养院患者因双脚严重形成斑块而入院。由于双脚斑块形成严重,浅表活检真菌和疥疮均为阴性。患者接受了双脚的手术诊断活检,从而确诊为挪威结痂性疥疮。随后进行了第二次手术清创,以清除广泛的斑块形成,并辅助口服伊维菌素和外用氯菊酯治疗。患者随后完全康复并出院回到疗养院。在治疗后2个月和6个月时,患者疥疮未再复发,手术伤口愈合良好。本病例报告表明,手术清创在治疗挪威结痂性疥疮感染患者时可作为标准局部和口服药物的补充。

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