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常规术中肝脏超声检查不会影响胰腺腺癌的分期或术后肝复发。

Routine intraoperative hepatic sonography does not affect staging or postsurgical hepatic recurrence in pancreatic adenocarcinoma.

机构信息

Department of Radiology, Hofstra North Shore-Long Island Jewish School of Medicine, North Shore University Medical Center, 300 Community Dr, Manhasset, NY 11030 USA.

出版信息

J Ultrasound Med. 2014 Jan;33(1):47-51. doi: 10.7863/ultra.33.1.47.

Abstract

OBJECTIVES

The purpose of this study was to evaluate the utility of intraoperative sonography of the liver in the staging of pancreatic adenocarcinoma and its impact on the rate of postoperative tumor recurrence in the liver.

METHODS

We performed a retrospective analysis of the rate in which intraoperative sonography of the liver changed surgical management in 470 surgical candidates with pancreatic adenocarcinoma. In postsurgical patients, we performed a χ(2) analysis to examine whether the patients who underwent hepatic intraoperative sonography had a lower rate of recurrent disease in the liver within the first 6 months of surgery compared to patients who did not undergo the procedure.

RESULTS

Hepatic intraoperative sonography affected management in less than 1% of cases, detecting 1 unsuspected liver metastasis in 470 surgical patients with pancreatic adenocarcinoma. Of 3 patients with equivocal liver lesions identified on preoperative computed tomography or magnetic resonance imaging, hepatic intraoperative sonography excluded metastasis and cleared all the patients for surgical resection. There was no significant difference in postoperative liver recurrence between the group of patients who received intraoperative sonography before resection and patients who did not have the procedure done (P > .99).

CONCLUSIONS

Routine intraoperative sonography of the liver does not affect staging of pancreatic adenocarcinoma. It may be useful for evaluating equivocal lesions.

摘要

目的

本研究旨在评估术中肝脏超声在胰腺腺癌分期中的应用价值及其对术后肝脏肿瘤复发率的影响。

方法

我们对 470 例胰腺腺癌手术患者的术中肝脏超声改变手术管理的比率进行了回顾性分析。在术后患者中,我们进行了 χ(2)分析,以检查与未行该手术的患者相比,行术中肝脏超声检查的患者在术后 6 个月内肝脏复发疾病的比率是否较低。

结果

术中肝脏超声检查在不到 1%的病例中影响了治疗方案,在 470 例胰腺腺癌手术患者中发现了 1 例术前 CT 或 MRI 未发现的肝转移灶。在术前 CT 或 MRI 检查发现的 3 例肝脏可疑病变中,术中肝脏超声检查排除了转移灶,并使所有患者获得手术切除的机会。行与不行术中超声检查的两组患者术后肝脏复发率无显著差异(P>.99)。

结论

常规术中肝脏超声检查不会影响胰腺腺癌的分期。它可能对评估可疑病变有用。

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