K121Q ENPP1/PC-1基因多态性与北印度人群的胰岛素抵抗相关。 - Suppr

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超能文献

K121Q ENPP1/PC-1 gene polymorphism is associated with insulin resistance in a North Indian population.

作者信息

Prakash Jai, Mittal Balraj, Awasthi Shally, Agarwal C G, Srivastava Neena

机构信息

Department of Physiology, King George's Medical University, Lucknow 226 003, India.

出版信息

J Genet. 2013 Dec;92(3):571-6. doi: 10.1007/s12041-013-0287-2.

DOI:10.1007/s12041-013-0287-2

PMID:24371178

Abstract

摘要

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本文引用的文献

Reconstructing Indian population history.重构印度人口历史。

Nature. 2009 Sep 24;461(7263):489-94. doi: 10.1038/nature08365.

The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities.膜糖蛋白浆细胞抗原1/外核苷酸焦磷酸酶磷酸二酯酶1在胰岛素抵抗及相关异常发病机制中的作用

Endocr Rev. 2008 Feb;29(1):62-75. doi: 10.1210/er.2007-0004. Epub 2008 Jan 16.

The Q121/Q121 genotype of ENPP1/PC-1 is associated with lower BMI in non-diabetic whites.ENPP1/PC-1的Q121/Q121基因型与非糖尿病白人较低的体重指数相关。

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The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction.ENPP1/PC-1基因的K121Q多态性与胰岛素抵抗/致动脉粥样硬化表型相关，包括2型糖尿病和心肌梗死的早发。

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Obes Res. 2004 Nov;12(11):1805-13. doi: 10.1038/oby.2004.224.

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