细胞因子和趋化因子在刺激性接触性皮炎中的作用。
Cytokines and chemokines in irritant contact dermatitis.
机构信息
Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland.
Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland ; Department of Dermatology, Mie University Graduate School of Medicine, Tsu, Mie 514-8507, Japan.
出版信息
Mediators Inflamm. 2013;2013:916497. doi: 10.1155/2013/916497. Epub 2013 Nov 25.
Irritant contact dermatitis is a result of activated innate immune response to various external stimuli and consists of complex interplay which involves skin barrier disruption, cellular changes, and release of proinflammatory mediators. In this review, we will focus on key cytokines and chemokines involved in the pathogenesis of irritant contact dermatitis and also contrast the differences between allergic contact dermatitis and irritant contact dermatitis.
刺激性接触性皮炎是对各种外部刺激物激活固有免疫反应的结果，其涉及复杂的相互作用，包括皮肤屏障破坏、细胞变化和促炎介质的释放。在这篇综述中，我们将重点关注参与刺激性接触性皮炎发病机制的关键细胞因子和趋化因子，并对比变应性接触性皮炎和刺激性接触性皮炎之间的差异。
Zotero 插件