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约旦患者白塞病的眼部表现

Ocular manifestations of Behçet's disease in Jordanian patients.

作者信息

Abu-Ameerh Mohammed A, Mohammed Sawsan F, Mohammad Mona T, Ababneh Osama H, Al-Bdour Muawyah D

机构信息

Ophthalmology Department, Jordan University Hospital, Amman, Jordan.

出版信息

Saudi J Ophthalmol. 2013 Oct;27(4):247-51. doi: 10.1016/j.sjopt.2013.06.012. Epub 2013 Jul 1.

DOI:10.1016/j.sjopt.2013.06.012
PMID:24371419
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3841248/
Abstract

PURPOSE

To study the prevalence, manifestations and severity of ocular involvement of Behçet's disease in Jordanian patients.

METHODS

The study population consisted of 43 patients diagnosed to have Behçet's disease through Rheumatologist's examinations conducted at Jordan University Hospital between January 2002 and July 2009. The sample involved patients who displayed ocular manifestations. This included 18 patients; 12 males and 6 females with a mean age of 35 years (SD = 17.26). Ophthalmological examinations and retrospective analysis of medical files were carried on.

RESULTS

Ocular manifestations were seen in 41.9% of patients. The most common manifestation for Behçet's disease was vitritis with a prevalence of 55.6%, followed by anterior uveitis and retinal vasculitis (50% for each). On the other hand, the most frequent complications involved were cataract, cystoid macular edema (CMO), posterior synechiae and glaucoma with a prevalence of (44.4%), (33.3%), (11.1%) and (5.6%), respectively.

CONCLUSION

The prevalence and severity of ocular lesions in Behçet's disease is relatively low in Jordanian patients. This result indicates that early diagnoses and intervention might delay or even prevent vision loss for those patients.

摘要

目的

研究约旦患者白塞病眼部受累的患病率、表现及严重程度。

方法

研究对象为2002年1月至2009年7月在约旦大学医院经风湿病学家检查确诊为白塞病的43例患者。样本包括有眼部表现的患者。其中有18例患者,12例男性和6例女性,平均年龄35岁(标准差=17.26)。进行了眼科检查并对病历进行回顾性分析。

结果

41.9%的患者出现眼部表现。白塞病最常见的表现是葡萄膜炎,患病率为55.6%,其次是前葡萄膜炎和视网膜血管炎(各为50%)。另一方面,最常见的并发症分别为白内障、黄斑囊样水肿(CMO)、后粘连和青光眼,患病率分别为(44.4%)、(33.3%)、(11.1%)和(5.6%)。

结论

约旦患者白塞病眼部病变的患病率和严重程度相对较低。这一结果表明,早期诊断和干预可能会延缓甚至预防这些患者的视力丧失。

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Saliva and Serum Cytokine Profiles During Oral Ulceration in Behçet's Disease.贝切特病口腔溃疡期间的唾液和血清细胞因子谱。
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[Ocular manifestations of Behçet's disease].[白塞病的眼部表现]
Rev Med Interne. 2010 Aug;31(8):545-50. doi: 10.1016/j.revmed.2009.04.014. Epub 2010 Apr 21.
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Behçet's Uveitis.白塞氏葡萄膜炎
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Behcet's disease: from East to West.白塞病:从东到西。
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Behçet's disease: ocular effects and treatment.白塞病:眼部影响与治疗
Prog Retin Eye Res. 2008 Jan;27(1):111-36. doi: 10.1016/j.preteyeres.2007.09.002. Epub 2007 Nov 26.
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Br J Ophthalmol. 2007 Dec;91(12):1579-82. doi: 10.1136/bjo.2007.123554.
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Clinical features of chinese patients with Behçet's disease.中国白塞病患者的临床特征。
Ophthalmology. 2008 Feb;115(2):312-318.e4. doi: 10.1016/j.ophtha.2007.04.056. Epub 2007 Aug 10.
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Behçet's syndrome: disease manifestations, management, and advances in treatment.白塞病:疾病表现、管理及治疗进展
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Neovascularization of the optic disc in Behçet's disease.白塞病视盘的新生血管形成。
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