Abu-Ameerh Mohammed A, Mohammed Sawsan F, Mohammad Mona T, Ababneh Osama H, Al-Bdour Muawyah D
Ophthalmology Department, Jordan University Hospital, Amman, Jordan.
Saudi J Ophthalmol. 2013 Oct;27(4):247-51. doi: 10.1016/j.sjopt.2013.06.012. Epub 2013 Jul 1.
To study the prevalence, manifestations and severity of ocular involvement of Behçet's disease in Jordanian patients.
The study population consisted of 43 patients diagnosed to have Behçet's disease through Rheumatologist's examinations conducted at Jordan University Hospital between January 2002 and July 2009. The sample involved patients who displayed ocular manifestations. This included 18 patients; 12 males and 6 females with a mean age of 35 years (SD = 17.26). Ophthalmological examinations and retrospective analysis of medical files were carried on.
Ocular manifestations were seen in 41.9% of patients. The most common manifestation for Behçet's disease was vitritis with a prevalence of 55.6%, followed by anterior uveitis and retinal vasculitis (50% for each). On the other hand, the most frequent complications involved were cataract, cystoid macular edema (CMO), posterior synechiae and glaucoma with a prevalence of (44.4%), (33.3%), (11.1%) and (5.6%), respectively.
The prevalence and severity of ocular lesions in Behçet's disease is relatively low in Jordanian patients. This result indicates that early diagnoses and intervention might delay or even prevent vision loss for those patients.
研究约旦患者白塞病眼部受累的患病率、表现及严重程度。
研究对象为2002年1月至2009年7月在约旦大学医院经风湿病学家检查确诊为白塞病的43例患者。样本包括有眼部表现的患者。其中有18例患者,12例男性和6例女性,平均年龄35岁(标准差=17.26)。进行了眼科检查并对病历进行回顾性分析。
41.9%的患者出现眼部表现。白塞病最常见的表现是葡萄膜炎,患病率为55.6%,其次是前葡萄膜炎和视网膜血管炎(各为50%)。另一方面,最常见的并发症分别为白内障、黄斑囊样水肿(CMO)、后粘连和青光眼,患病率分别为(44.4%)、(33.3%)、(11.1%)和(5.6%)。
约旦患者白塞病眼部病变的患病率和严重程度相对较低。这一结果表明,早期诊断和干预可能会延缓甚至预防这些患者的视力丧失。