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妊娠期免疫性血小板减少症(ITP)的治疗选择

Therapeutic Options for Immune Thrombocytopenia (ITP) During Pregnancy.

作者信息

Nicolescu Anca, Vladareanu Ana Maria, Voican Irina, Onisai Minodora, Vladareanu Radu

机构信息

Emergency University Hospital, Department of Hematology, Bucarest, Romania.

Elias Emergency University Hospital, Department of Obstetrics-Gynecology, Bucharest, Romania.

出版信息

Maedica (Bucur). 2013 Jun;8(2):182-8.

Abstract

The incidence of ITP during pregnancy is low. When ITP is suspected it is necessary to perform an extended set of clinical and biological investigations in order to determine the etiology of thrombocytopenia, as the diagnosis of ITP is a process of exclusion, because there is no sensitive and specific diagnostic test so far. The treatment for ITP during pregnancy represents a challenge, being necessary in the cases selected according to the obstetrical indications, to the degree of maternal thrombocytopenia and to the extent of the hemorrhagic syndrome, as well as according to the adverse reactions of the treatment on the mother and fetus.

摘要

妊娠期间特发性血小板减少性紫癜(ITP)的发病率较低。当怀疑患有ITP时,有必要进行一系列广泛的临床和生物学检查,以确定血小板减少的病因,因为ITP的诊断是一个排除过程,因为目前尚无敏感且特异的诊断测试。妊娠期间ITP的治疗是一项挑战,根据产科指征、母体血小板减少程度、出血综合征的范围以及治疗对母亲和胎儿的不良反应,在选定的病例中进行治疗是必要的。

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本文引用的文献

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Thrombocytopenia in pregnancy.妊娠血小板减少症。
Hematology Am Soc Hematol Educ Program. 2010;2010:397-402. doi: 10.1182/asheducation-2010.1.397.
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Laparoscopic surgery during pregnancy.妊娠期腹腔镜手术
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How I treat idiopathic thrombocytopenic purpura (ITP).我如何治疗特发性血小板减少性紫癜(ITP)。
Blood. 2005 Oct 1;106(7):2244-51. doi: 10.1182/blood-2004-12-4598. Epub 2005 Jun 7.
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Intravenous anti-D as a treatment for immune thrombocytopenic purpura (ITP) during pregnancy.
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