Kumar Verma Roshan, Shivaprakash M R, Shanker Amit, Panda Naresh K
Department of Otolaryngology Head and Neck Surgery, PGIMER, Chandigarh 160012, India.
Department of Medical Microbiology, PGIMER, Chandigarh 160012, India.
Med Mycol Case Rep. 2012 Aug 4;1(1):59-62. doi: 10.1016/j.mmcr.2012.07.004. eCollection 2012.
Basidiobolomycosis is a rare chronic subcutaneous infection caused by Basidiobolus ranarum. The disease usually occurs in children, less often in adolescent and rarely in adults. Males are more frequently affected than females. We report a case of subcutaneous zygomycosis of head and neck region caused by B. ranaram, in an immunocompetent adult female presenting with nontender firm swelling over the nape of neck and temporo-parietal region. The diagnosis was confirmed by histopathology, microbiology (culture) and DNA sequencing of molecular technique (sequencing). The patient was successfully treated with amphotericin B and potassium iodide.
蛙粪霉病是一种由蛙粪霉引起的罕见慢性皮下感染。该疾病通常发生于儿童,青少年较少见,成人则罕见。男性比女性更易受累。我们报告一例由蛙粪霉引起的头颈部皮下接合菌病,患者为一名免疫功能正常的成年女性,表现为颈后和颞顶区域无痛性坚实肿胀。通过组织病理学、微生物学(培养)以及分子技术(测序)的DNA测序确诊。患者接受两性霉素B和碘化钾治疗后痊愈。