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本文引用的文献

1
Disseminated Geosmithia argillacea infection in a patient with gastrointestinal GvHD.一名患有胃肠道移植物抗宿主病的患者发生播散性泥质地丝菌感染。
Bone Marrow Transplant. 2012 May;47(5):734-6. doi: 10.1038/bmt.2011.149. Epub 2011 Jul 25.
2
Geosmithia argillacea: an emerging cause of invasive mycosis in human chronic granulomatous disease.地霉属：人类慢性肉芽肿病侵袭性真菌感染的新病因。
Clin Infect Dis. 2011 Mar 15;52(6):e136-43. doi: 10.1093/cid/ciq250.
3
Emergence of disseminated infections due to Geosmithia argillacea in patients with chronic granulomatous disease receiving long-term azole antifungal prophylaxis.由于长期唑类抗真菌预防治疗的慢性肉芽肿病患者感染 Geosmithia argillacea 而出现播散性感染。
J Clin Microbiol. 2011 Apr;49(4):1681-3. doi: 10.1128/JCM.02456-10. Epub 2011 Jan 26.
4
Geosmithia argillacea: an emerging pathogen in patients with cystic fibrosis.地衣芽枝孢菌：囊性纤维化患者中的一种新出现的病原体。
J Clin Microbiol. 2010 Jul;48(7):2381-6. doi: 10.1128/JCM.00047-10. Epub 2010 May 12.
5
Isolation of the fungus Geosmithia argillacea in sputum of people with cystic fibrosis.从囊性纤维化患者的痰中分离出真菌 Geosmithia argillacea。
J Clin Microbiol. 2010 Jul;48(7):2615-7. doi: 10.1128/JCM.00184-10. Epub 2010 Apr 26.
6
Disseminated Scedosporium/Pseudallescheria infection after double-lung transplantation in patients with cystic fibrosis.囊性纤维化患者双肺移植后播散性节菱孢/拟青霉感染。
J Clin Microbiol. 2010 May;48(5):1978-82. doi: 10.1128/JCM.01840-09. Epub 2010 Mar 10.
7
Development of an oligonucleotide array for direct detection of fungi in sputum samples from patients with cystic fibrosis.用于直接检测囊性纤维化患者痰液样本中真菌的寡核苷酸阵列的开发。
J Clin Microbiol. 2009 Jan;47(1):142-52. doi: 10.1128/JCM.01668-08. Epub 2008 Nov 19.
8
Disseminated Scedosporium apiospermum infection in a cystic fibrosis patient after double-lung transplantation.一名囊性纤维化患者双肺移植后播散性尖端赛多孢菌感染
J Heart Lung Transplant. 2006 May;25(5):603-7. doi: 10.1016/j.healun.2005.12.011. Epub 2006 Mar 23.
9
UNITE: a database providing web-based methods for the molecular identification of ectomycorrhizal fungi.UNITE：一个提供基于网络的外生菌根真菌分子鉴定方法的数据库。
New Phytol. 2005 Jun;166(3):1063-8. doi: 10.1111/j.1469-8137.2005.01376.x.
10
Aspergillus infection in lung transplant recipients with cystic fibrosis: risk factors and outcomes comparison to other types of transplant recipients.患有囊性纤维化的肺移植受者的曲霉感染：危险因素及与其他类型移植受者的结局比较
Chest. 2003 Mar;123(3):800-8. doi: 10.1378/chest.123.3.800.

米卡芬净治疗一名囊性纤维化患者土栖地丝菌感染的临床及微生物学疗效

Clinical and microbiological efficacy of micafungin on Geosmithia argillacea infection in a cystic fibrosis patient.

作者信息

Marguet Christophe, Favennec Loïc, Matray Olivier, Bertout Sébastien, Giraud Sandrine, Couderc Laure, Zouhair Rachid, Leguillon Christine, Gargala Gilles, Ballet Jean-J Jacques, Bouchara Jean-Philippe

机构信息

Unité de pneumologie et d'allergologie pédiatrique, Département de pédiatrie médicale, Centre Hospitalier Universitaire and Université de Rouen, 1, rue de Germont, 76031 Rouen, France.

Laboratoire de Parasitologie-mycologie, EA 3800, Centre Hospitalier Universitaire and Université de Rouen, 1, rue de Germont, 76031 Rouen, France.

出版信息

Med Mycol Case Rep. 2012 Sep 12;1(1):79-81. doi: 10.1016/j.mmcr.2012.08.004. eCollection 2012.

DOI:10.1016/j.mmcr.2012.08.004
PMID:24371745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3854624/
Abstract

Cystic fibrosis (CF) patients are at high risk of colonization of the airways by a number of fungi, including the emerging opportunistic fungus Geosmithia argillacea. We report the eradication of respiratory G. argillacea associated with clinical resolution of severe symptoms by high-dose and prolonged micafungin therapy in a young CF patient.

摘要

囊性纤维化（CF）患者气道被多种真菌定植的风险很高，包括新出现的机会性真菌泥质地丝霉。我们报告了在一名年轻的CF患者中，通过高剂量和延长米卡芬净治疗根除了与严重症状临床缓解相关的呼吸道泥质地丝霉。