米卡芬净治疗一名囊性纤维化患者土栖地丝菌感染的临床及微生物学疗效
Clinical and microbiological efficacy of micafungin on Geosmithia argillacea infection in a cystic fibrosis patient.
作者信息
Marguet Christophe, Favennec Loïc, Matray Olivier, Bertout Sébastien, Giraud Sandrine, Couderc Laure, Zouhair Rachid, Leguillon Christine, Gargala Gilles, Ballet Jean-J Jacques, Bouchara Jean-Philippe
机构信息
Unité de pneumologie et d'allergologie pédiatrique, Département de pédiatrie médicale, Centre Hospitalier Universitaire and Université de Rouen, 1, rue de Germont, 76031 Rouen, France.
Laboratoire de Parasitologie-mycologie, EA 3800, Centre Hospitalier Universitaire and Université de Rouen, 1, rue de Germont, 76031 Rouen, France.
出版信息
Med Mycol Case Rep. 2012 Sep 12;1(1):79-81. doi: 10.1016/j.mmcr.2012.08.004. eCollection 2012.
Abstract
Cystic fibrosis (CF) patients are at high risk of colonization of the airways by a number of fungi, including the emerging opportunistic fungus Geosmithia argillacea. We report the eradication of respiratory G. argillacea associated with clinical resolution of severe symptoms by high-dose and prolonged micafungin therapy in a young CF patient.
摘要
囊性纤维化（CF）患者气道被多种真菌定植的风险很高，包括新出现的机会性真菌泥质地丝霉。我们报告了在一名年轻的CF患者中，通过高剂量和延长米卡芬净治疗根除了与严重症状临床缓解相关的呼吸道泥质地丝霉。
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