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囊性纤维化患者双肺移植后播散性节菱孢/拟青霉感染。

Disseminated Scedosporium/Pseudallescheria infection after double-lung transplantation in patients with cystic fibrosis.

机构信息

Laboratoire de Parasitologie-Mycologie, CHU de Nantes, Hôtel Dieu, 9 Quai Moncousu, 44093 Nantes Cedex 1, France.

出版信息

J Clin Microbiol. 2010 May;48(5):1978-82. doi: 10.1128/JCM.01840-09. Epub 2010 Mar 10.

Abstract

We report a case of disseminated Scedosporium/Pseudallescheria infection due to Pseudallescheria boydii sensu stricto after lung transplantation in a patient with cystic fibrosis. Dissemination occurred under voriconazole. Despite surgery and combination therapy with voriconazole, caspofungin, and terbinafine, the patient died 8 months after transplantation. Previously reported cases are reviewed.

摘要

我们报告了一例囊性纤维化肺移植患者发生播散性 Scedosporium/Pseudallescheria 感染,由 Pseudallescheria boydii sensu stricto 引起。伏立康唑治疗期间发生播散。尽管进行了手术和伏立康唑、卡泊芬净和特比萘芬联合治疗,但患者在移植后 8 个月死亡。我们回顾了之前报道的病例。

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