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本文引用的文献

1
Detection of occult Scedosporium species in respiratory tract specimens from patients with cystic fibrosis by use of selective media.应用选择性培养基检测囊性纤维化患者呼吸道标本中的隐匿拟青霉属。
J Clin Microbiol. 2010 Jan;48(1):314-6. doi: 10.1128/JCM.01470-09. Epub 2009 Nov 11.
2
Scedosporium prolificans osteomyelitis in an immunocompetent child treated with a novel agent, hexadecylphospocholine (miltefosine), in combination with terbinafine and voriconazole: a case report.用新型药物十六烷基磷酰胆碱（米替福新）联合特比萘芬和伏立康唑治疗免疫功能正常儿童的多育赛多孢菌骨髓炎：一例报告
Clin Infect Dis. 2009 May 1;48(9):1257-61. doi: 10.1086/597772.
3
Voriconazole pharmacokinetic variability in cystic fibrosis lung transplant patients.囊性纤维化肺移植患者中伏立康唑的药代动力学变异性
Transpl Infect Dis. 2009 Jun;11(3):211-9. doi: 10.1111/j.1399-3062.2009.00384.x. Epub 2009 Mar 17.
4
Scedosporium prolificans: an emerging pathogen in France?多育赛多孢：法国一种新出现的病原体？
Med Mycol. 2009 Jun;47(4):343-50. doi: 10.1080/13693780802454761. Epub 2008 Dec 12.
5
EUCAST Technical Note on the method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for conidia-forming moulds.欧洲抗菌药物敏感性试验委员会关于测定产分生孢子霉菌抗真菌药物肉汤稀释最低抑菌浓度方法的技术说明。
Clin Microbiol Infect. 2008 Oct;14(10):982-4. doi: 10.1111/j.1469-0691.2008.02086.x.
6
Different virulence of the species of the Pseudallescheria boydii complex.波氏假阿利什菌复合体不同种的毒力差异。
Med Mycol. 2009 Jun;47(4):371-4. doi: 10.1080/13693780802256539. Epub 2008 Jul 9.
7
Fungal infections after lung transplantation.肺移植后的真菌感染
Transplant Rev (Orlando). 2008 Apr;22(2):89-104. doi: 10.1016/j.trre.2007.12.007.
8
Treatment of scedosporiosis with voriconazole: clinical experience with 107 patients.伏立康唑治疗足放线病菌病：107例患者的临床经验
Antimicrob Agents Chemother. 2008 May;52(5):1743-50. doi: 10.1128/AAC.01388-07. Epub 2008 Jan 22.
9
Infections caused by Scedosporium spp.由瓶霉属真菌引起的感染
Clin Microbiol Rev. 2008 Jan;21(1):157-97. doi: 10.1128/CMR.00039-07.
10
In vitro activities of 35 double combinations of antifungal agents against Scedosporium apiospermum and Scedosporium prolificans.35种抗真菌药物双重组合对波氏足分支霉和多育足分支霉的体外活性
Antimicrob Agents Chemother. 2008 Mar;52(3):1136-9. doi: 10.1128/AAC.01160-07. Epub 2008 Jan 14.

囊性纤维化患者双肺移植后播散性节菱孢/拟青霉感染。

Disseminated Scedosporium/Pseudallescheria infection after double-lung transplantation in patients with cystic fibrosis.

机构信息

Laboratoire de Parasitologie-Mycologie, CHU de Nantes, Hôtel Dieu, 9 Quai Moncousu, 44093 Nantes Cedex 1, France.

出版信息

J Clin Microbiol. 2010 May;48(5):1978-82. doi: 10.1128/JCM.01840-09. Epub 2010 Mar 10.

DOI:10.1128/JCM.01840-09
PMID:20220160
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2863884/
Abstract

We report a case of disseminated Scedosporium/Pseudallescheria infection due to Pseudallescheria boydii sensu stricto after lung transplantation in a patient with cystic fibrosis. Dissemination occurred under voriconazole. Despite surgery and combination therapy with voriconazole, caspofungin, and terbinafine, the patient died 8 months after transplantation. Previously reported cases are reviewed.

摘要

我们报告了一例囊性纤维化肺移植患者发生播散性 Scedosporium/Pseudallescheria 感染，由 Pseudallescheria boydii sensu stricto 引起。伏立康唑治疗期间发生播散。尽管进行了手术和伏立康唑、卡泊芬净和特比萘芬联合治疗，但患者在移植后 8 个月死亡。我们回顾了之前报道的病例。