脾切除术作为急性髓系白血病辅助使用干扰素γ和两性霉素脂质体治疗后播散性霉菌感染的一种有效减瘤疗法。
Splenectomy as an effective debulking therapy for disseminated mould infection in acute myeloid leukaemia following adjuvant therapy with interferon gamma and liposomal amphotericin.
作者信息
Latif Anne-Louise, Harper Chrsitina, Macdonald Ian, Morrison Anne
机构信息
Department of Haematology and Blood Transfusion, Southern General Hospital, 1345 Govan Road, Glasgow G51 4 TF, UK.
Department of Pathology, Southern General Hospital, Glasgow G51 4 TF, UK.
出版信息
Med Mycol Case Rep. 2012 Sep 10;1(1):82-4. doi: 10.1016/j.mmcr.2012.08.005. eCollection 2012.
Abstract
Invasive fungal infection is a major cause of morbidity and mortality in patients receiving treatment for Acute Myeloid Leukaemia (AML). Herein, we report a case of a 21 year old woman with an extremely resistant Fusarium species that responded to the addition of interferon gamma to her medical therapy, subsequently allowing definitive debulking surgery of her invasive Fusarium infection to be undertaken.
摘要
侵袭性真菌感染是接受急性髓系白血病（AML）治疗患者发病和死亡的主要原因。在此，我们报告一例21岁女性病例，其感染了一种极具耐药性的镰刀菌属菌种，在其治疗方案中加入γ干扰素后病情出现好转，随后得以对其侵袭性镰刀菌感染进行确定性减瘤手术。
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