Makuta Gladys, Chrysafis Manolis, Lam Thomas
Academic Urology Unit, University of Aberdeen.
Nurs Times. 2013;109(44):16, 18-9.
Catheter-associated urinary tract infections (CAUTI) are a major cause of morbidity in hospitals worldwide. Urethral catheters coated with antimicrobial substances such as silver alloy and nitrofurazone were introduced to reduce CAUTI. A previous Cochrane review reported that antimicrobial-coated or impregnated catheters may reduce the number of asymptomatic bacteriuria present but it was uncertain whether they reduced CAUTI. The Catheter Trial compared these and standard catheters for short-term use in NHS hospitals. Results showed silver alloy-coated catheters did not reduce symptomatic CAUTI compared with standard catheters; nitrofurazone-impregnated catheters had borderline clinical benefit in reducing symptomatic CAUTI. The findings do not support the routine use of antimicrobial-coated or impregnated catheters for patients in hospital who need short-term catheters. Instead, health professionals should focus on simple preventive strategies and reducing the need for catheterisation.
导尿管相关尿路感染（CAUTI）是全球医院中发病的主要原因。为减少CAUTI，引入了涂有抗菌物质（如银合金和呋喃西林）的尿道导管。之前的Cochrane综述报告称，抗菌涂层或浸渍导管可能会减少无症状菌尿的数量，但不确定它们是否能减少CAUTI。导管试验在英国国家医疗服务体系（NHS）医院对这些导管与标准导管进行了短期使用比较。结果显示，与标准导管相比，银合金涂层导管并未减少有症状的CAUTI；呋喃西林浸渍导管在减少有症状的CAUTI方面有边缘性临床益处。这些发现不支持对医院中需要短期导尿管的患者常规使用抗菌涂层或浸渍导管。相反，卫生专业人员应专注于简单的预防策略并减少导尿需求。
