• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

轴突与其施万细胞髓磷脂 - 蛋白质鞘之间的电磁感应。

Electromagnetic induction between axons and their schwann cell myelin-protein sheaths.

作者信息

Goodman G, Bercovich D

机构信息

Galil Genetic Analysis, Kazerin 12900, Israel.

出版信息

J Integr Neurosci. 2013 Dec;12(4):475-89. doi: 10.1142/S0219635213500295. Epub 2013 Nov 15.

DOI:10.1142/S0219635213500295
PMID:24372067
Abstract

Two concepts have long dominated vertebrate nerve electrophysiology: (a) Schwann cell-formed myelin sheaths separated by minute non-myelinated nodal gaps and spiraling around axons of peripheral motor nerves reduce current leakage during propagation of trains of axon action potentials; (b) "jumping" by action potentials between successive nodes greatly increases signal conduction velocity. Long-held and more recent assumptions and issues underlying those concepts have been obscured by research emphasis on axon-sheath biochemical symbiosis and nerve regeneration. We hypothesize: mutual electromagnetic induction in the axon-glial sheath association, is fundamental in signal conduction in peripheral and central myelinated axons, explains the g-ratio and is relevant to animal navigation.

摘要

长期以来,有两个概念主导着脊椎动物神经电生理学:(a) 施万细胞形成的髓鞘由微小的无髓鞘节点间隙隔开,并围绕外周运动神经的轴突呈螺旋状排列,可减少轴突动作电位序列传播过程中的电流泄漏;(b) 动作电位在连续节点之间的“跳跃”极大地提高了信号传导速度。长期以来以及最近关于这些概念的假设和问题,都因对轴突-髓鞘生化共生和神经再生的研究重点而变得模糊不清。我们假设:轴突-胶质鞘关联中的相互电磁感应,是外周和中枢有髓轴突信号传导的基础,解释了g值比,并且与动物导航相关。

相似文献

1
Electromagnetic induction between axons and their schwann cell myelin-protein sheaths.轴突与其施万细胞髓磷脂 - 蛋白质鞘之间的电磁感应。
J Integr Neurosci. 2013 Dec;12(4):475-89. doi: 10.1142/S0219635213500295. Epub 2013 Nov 15.
2
Do olfactory glia have advantages over Schwann cells for CNS repair?嗅神经胶质细胞在中枢神经系统修复方面比施万细胞有优势吗?
J Neurosci Res. 1997 Dec 1;50(5):665-72. doi: 10.1002/(SICI)1097-4547(19971201)50:5<665::AID-JNR4>3.0.CO;2-F.
3
What is the optimal distribution of myelin along a single axon?髓磷脂沿单个轴突的最佳分布是怎样的?
Neurosci Lett. 2017 Sep 29;658:97-101. doi: 10.1016/j.neulet.2017.08.037. Epub 2017 Aug 31.
4
The evolution of vertebrate and invertebrate myelin: a theoretical computational study.脊椎动物和无脊椎动物髓磷脂的进化:一项理论计算研究。
J Comput Neurosci. 2015 Jun;38(3):521-38. doi: 10.1007/s10827-015-0552-x. Epub 2015 Apr 2.
5
The neurotrophin receptor p75NTR in Schwann cells is implicated in remyelination and motor recovery after peripheral nerve injury.雪旺细胞中的神经营养因子受体p75NTR与周围神经损伤后的髓鞘再生和运动恢复有关。
Glia. 2007 Aug 15;55(11):1199-208. doi: 10.1002/glia.20533.
6
Distribution of sodium channels in chronically demyelinated spinal cord axons: immuno-ultrastructural localization and electrophysiological observations.慢性脱髓鞘脊髓轴突中钠通道的分布:免疫超微结构定位及电生理观察
Brain Res. 1991 Mar 22;544(1):59-70. doi: 10.1016/0006-8993(91)90885-y.
7
Rapid conduction and the evolution of giant axons and myelinated fibers.快速传导以及巨轴突和有髓纤维的进化。
Curr Biol. 2007 Jan 9;17(1):R29-35. doi: 10.1016/j.cub.2006.11.042.
8
Molecular dissection of the myelinated axon.有髓轴突的分子剖析
Ann Neurol. 1993 Feb;33(2):121-36. doi: 10.1002/ana.410330202.
9
Neuron-glia signaling and the protection of axon function by Schwann cells.神经元-胶质细胞信号传递与施万细胞对轴突功能的保护。
J Peripher Nerv Syst. 2010 Mar;15(1):10-6. doi: 10.1111/j.1529-8027.2010.00247.x.
10
Myelin-axon relationships established by rat vagal Schwann cells deep to the brainstem surface.大鼠迷走神经雪旺细胞在脑干表面深处建立的髓鞘-轴突关系。
J Comp Neurol. 1991 Feb 8;304(2):253-60. doi: 10.1002/cne.903040208.

引用本文的文献

1
Electrical stimulation promotes regeneration of injured oculomotor nerves in dogs.电刺激促进犬动眼神经损伤后的再生。
Neural Regen Res. 2016 Oct;11(10):1666-1669. doi: 10.4103/1673-5374.193248.