Department of Gynecology and Obstetrics, Herlev Hospital, University of Copenhagen, Copenhagen.
Acta Obstet Gynecol Scand. 2014 Feb;93(2):209-12. doi: 10.1111/aogs.12283. Epub 2013 Dec 24.
Urethral injection therapy for treatment of stress urinary incontinence has been in use for years, but only a few long-term follow-up studies have been published. Twenty-five women, injected with polyacrylamide hydrogel 8 years earlier, were invited for follow-up. Twenty-four could be contacted; 15 had had no further treatment, seven had been re-operated with placement of mid-urethral slings, and two had been re-injected with polyacrylamide hydrogel. Eleven women attended for objective examination; all non-attenders were interviewed by telephone. Subjectively, in 44% the stress incontinence was cured or much improved, with a positive outcome according to the King's Health Questionnaire. Objectively, all patients had visible polyacrylamide hydrogel deposits on vaginal ultrasonography. No local adverse reactions were seen in the vaginal mucosa. The results of a later mid-urethral sling were unaffected by previous polyacrylamide hydrogel injection.
尿道注射疗法治疗压力性尿失禁已有多年历史，但仅有少数长期随访研究发表。25 名 8 年前接受过聚丙烯酰胺水凝胶注射的女性接受了随访。24 名可以联系到；15 名未接受进一步治疗，7 名接受了中尿道吊带再手术，2 名接受了聚丙烯酰胺水凝胶再注射。11 名女性接受了客观检查；所有未到场者均通过电话接受了采访。主观上，44%的压力性尿失禁得到治愈或明显改善，根据 King 健康问卷，结果为阳性。客观上，所有患者的阴道超声检查均可见聚丙烯酰胺水凝胶沉积。阴道黏膜未见局部不良反应。先前的聚丙烯酰胺水凝胶注射对后期中尿道吊带的结果没有影响。
