[Management of preterm prelabor rupture of membranes with respect to the inflammatory complications - our experiences].

OBJECTIVE

Preterm prelabor rupture of membranes is responsible for approximately one third of all preterm deliveries. The most common complications associated with this pregnancy pathology are microbial invasion of the amniotic cavity, intraamniotic inflammation, intraamniotic infection and histological chorioamnionitis. This article explains these complicatioss and their relation to the optimal management of preterm prelabor rupture of membranes.

DESIGN

Overview study.

SETTING

Department of Obstetrics and Gynecology, Charles University in Prague, Faculty of Medicine and University Hospital Hradec Kralove.

METHODS

To analyze current knowledge and our own experiences regarding inflammatory complications of preterm prelabor rupture of membranes.

CONCLUSION

Inflammatory complications of preterm prelabor rupture of membranes are associated with risk of development of early onset sepsis. Nevertheless, gestational age is a main confounder affecting neonatal morbidity and mortality.