一种在果蝇眼睛感光细胞R7中表达的视紫红质基因：与其他信号转导分子的同源性。
A rhodopsin gene expressed in photoreceptor cell R7 of the Drosophila eye: homologies with other signal-transducing molecules.
作者信息
Zuker C S, Montell C, Jones K, Laverty T, Rubin G M
出版信息
J Neurosci. 1987 May;7(5):1550-7. doi: 10.1523/JNEUROSCI.07-05-01550.1987.
Abstract
We have isolated an opsin gene from D. melanogaster that is expressed in the ultraviolet-sensitive photoreceptor cell R7 of the Drosophila compound eye. This opsin gene contains no introns and encodes a 383 amino acid polypeptide that is approximately 35% homologous to the blue absorbing ninaE and Rh2 opsins, which are expressed in photoreceptor cells R1-6 and R8, respectively. Amino acid homologies between these different opsins and other signal-transducing molecules suggest an important role for the conserved domains of rhodopsin in the transduction of extracellular signals.
摘要
我们从黑腹果蝇中分离出一个视蛋白基因，该基因在果蝇复眼的紫外线敏感光感受器细胞R7中表达。这个视蛋白基因不含内含子，编码一个383个氨基酸的多肽，该多肽与分别在光感受器细胞R1-6和R8中表达的吸收蓝光的ninaE和Rh2视蛋白大约有35%的同源性。这些不同视蛋白与其他信号转导分子之间的氨基酸同源性表明，视紫红质的保守结构域在细胞外信号转导中起重要作用。
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