Mazzotta Gabriella M, Damulewicz Milena, Cusumano Paola
Department of Biology, University of Padova, Padua, Italy.
Department of Cell Biology and Imaging, Jagiellonian University, Kraków, Poland.
Front Physiol. 2020 Sep 4;11:997. doi: 10.3389/fphys.2020.00997. eCollection 2020.
Sleep-like states have been described in and the mechanisms and factors that generate and define sleep-wake profiles in this model organism are being thoroughly investigated. Sleep is controlled by both circadian and homeostatic mechanisms, and environmental factors such as light, temperature, and social stimuli are fundamental in shaping and confining sleep episodes into the correct time of the day. Among environmental cues, light seems to have a prominent function in modulating the timing of sleep during the 24 h and, in this review, we will discuss the role of light inputs in modulating the distribution of the fly sleep-wake cycles. This phenomenon is of growing interest in the modern society, where artificial light exposure during the night is a common trait, opening the possibility to study as a model organism for investigating shift-work disorders.
在[具体内容未提及]中已经描述了类似睡眠的状态，并且正在对这种模式生物中产生和定义睡眠-觉醒模式的机制和因素进行深入研究。睡眠由昼夜节律和稳态机制共同控制，诸如光照、温度和社会刺激等环境因素对于将睡眠时段塑造并限制在一天中的正确时间至关重要。在环境线索中，光照似乎在调节24小时内的睡眠时机方面具有突出作用，在本综述中，我们将讨论光输入在调节果蝇睡眠-觉醒周期分布中的作用。这种现象在现代社会中越来越受到关注，夜间人工光照暴露是一种常见特征，这为将[果蝇]作为研究轮班工作障碍的模式生物进行研究提供了可能性。
