Diz Dios P
OMEQUI Research Group, School of Medicine and Dentistry, Santiago de Compostela University, Santiago de Compostela, Spain.
Oral Dis. 2014 May;20(4):325-8. doi: 10.1111/odi.12221. Epub 2014 Jan 13.
Antibiotic prophylaxis for infective endocarditis continues to be administered empirically, although its indications are ever more restrictive. Some expert committees have even suggested that antibiotic prophylaxis is unnecessary, rekindling the controversy between those who defend the scientific evidence and those working in clinical practice; in any case, this proposal will facilitate the undertaking of prospective placebo-controlled trials, so necessary to resolve this issue. In the meantime, the most prudent approach is to adopt the recommendations proposed by the expert committees in each country.
尽管感染性心内膜炎的抗生素预防指征越来越严格，但仍在凭经验使用。一些专家委员会甚至建议无需进行抗生素预防，这再次引发了支持科学证据者与临床从业者之间的争议；无论如何，这一提议将有助于开展前瞻性安慰剂对照试验，而这对于解决该问题是非常必要的。与此同时，最谨慎的做法是采纳各国专家委员会提出的建议。
