Morimont P, Frippiat F, Lancellotti P, Lambermont B
Service des Soins Intensifs Médicaux, CHU de Liège, Belgique.
Rev Med Liege. 2008 Nov;63(11):640-2.
Prophylaxis for infective endocarditis has been recommended on the basis of the supposed pathophysiology of the disease, although no randomised clinical trial has confirmed its efficacy. Bacteraemia resulting from daily activities is much more likely to cause infective endocarditis than bacteraemia associated with invasive medical procedures. As a result, recommendations for antibiotic prophylaxis tend now to be severely restricted.
尽管尚无随机临床试验证实其疗效，但基于感染性心内膜炎的假定病理生理学，人们一直推荐对其进行预防。日常活动导致的菌血症比与侵入性医疗操作相关的菌血症更有可能引起感染性心内膜炎。因此，现在抗生素预防的建议往往受到严格限制。
