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养老院中抗精神病药物的使用因精神科顾问而异。

Antipsychotic use in nursing homes varies by psychiatric consultant.

机构信息

*University of Massachusetts Medical School †Meyers Primary Care Institute, Worcester, MA ‡Qualidigm, Wethersfield, CT §Massachsuetts College of Pharmacy and Health Sciences, Worcester, MA.

出版信息

Med Care. 2014 Mar;52(3):267-71. doi: 10.1097/MLR.0000000000000076.

Abstract

BACKGROUND

The relationship between psychiatric consultation and antipsychotic prescribing in nursing homes (NH) is unknown.

OBJECTIVE

To identify the association between psychiatric consultant groups and NH-level antipsychotic prescribing after adjustment for resident case-mix and facility characteristics.

RESEARCH DESIGN AND SUBJECTS

Nested cross-sectional study of 60 NHs in a cluster randomized trial. We linked facility leadership surveys to October 2009-September 2010 Minimum Data Set, Nursing Home Compare, the US Census, and pharmacy dispensing data.

MEASURES

The main exposure is the psychiatric consultant group and the main outcome is NH-level prevalence of atypical antipsychotic use. We calculated annual means and interquartile ranges of NH-level antipsychotic use for each consultant group and arrayed consultant groups from lowest to highest prevalence. Generalized linear models were used to predict antipsychotic prescribing adjusting for resident case-mix and facility characteristics. Observed versus predicted antipsychotic prescribing levels were compared for each consultant group.

RESULTS

Seven psychiatric consultant groups served a range of 3-27 study facilities. Overall mean facility-level antipsychotic prescribing was 19.2%. Mean prevalence of antipsychotic prescribing ranged from 12.2% (SD, 5.8) in the lowest consultant group to 26.4% (SD, 3.6) in the highest group. All facilities served by the highest-ranked consultant group had observed antipsychotic levels exceeding the overall study mean with half exceeding predictions for on-label indications, whereas most facilities served by the lowest-ranked consultant group had observed levels below the overall study and predicted means.

CONCLUSIONS

Preliminary evidence suggests that psychiatric consultant groups affect NH antipsychotic prescribing independent of resident case-mix and facility characteristics.

摘要

背景

疗养院(NH)中精神科会诊与抗精神病药物处方之间的关系尚不清楚。

目的

在调整了居民病例组合和设施特征后,确定精神科顾问组与 NH 级抗精神病药物处方之间的关联。

研究设计和对象

一项嵌套的横断面研究,共纳入了一项集群随机试验中的 60 家 NH。我们将设施领导调查与 2009 年 10 月至 2010 年 9 月的最低数据组、疗养院比较、美国人口普查和药房配药数据进行了关联。

测量

主要暴露因素是精神科顾问组,主要结局是 NH 级别的非典型抗精神病药物使用率。我们计算了每个顾问组的 NH 级抗精神病药物使用的年平均值和四分位距,并按最低到最高的流行率排列了顾问组。使用广义线性模型调整居民病例组合和设施特征来预测抗精神病药物的处方。比较了每个顾问组的观察与预测的抗精神病药物使用水平。

结果

有七个精神科顾问组为 3 至 27 家研究机构提供服务。整体平均设施级抗精神病药物处方率为 19.2%。抗精神病药物处方的平均流行率范围从最低顾问组的 12.2%(标准差,5.8)到最高组的 26.4%(标准差,3.6)。由排名最高的顾问组服务的所有机构的观察到的抗精神病药物水平均超过了总体研究的平均值,其中一半超过了标签指示的预测值,而由排名最低的顾问组服务的大多数机构的观察到的水平均低于总体研究和预测值。

结论

初步证据表明,精神科顾问组独立于居民病例组合和设施特征影响 NH 抗精神病药物的处方。

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