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应用培养的自体口腔黏膜上皮细胞行男变女易性术:一项可行性、安全性和优越性的临床初步研究。

The use of cultured autologous oral epithelial cells for vaginoplasty in male-to-female transsexuals: a feasibility, safety, and advantageousness clinical pilot study.

机构信息

Rome and Perugia, Italy From the Departments of Plastic and Reconstructive Surgery and Experimental Medicine, Sapienza University of Rome; and the Department of Plastic and Reconstructive Surgery, University of Perugia.

出版信息

Plast Reconstr Surg. 2014 Jan;133(1):158-161. doi: 10.1097/01.prs.0000435844.95551.35.

DOI:10.1097/01.prs.0000435844.95551.35
PMID:24374675
Abstract

Various vaginoplasty methods in male-to-female transsexuals have been described, but none is ideal. The use of cultured autologous oral epithelium to cover the neovagina walls is presented. Six patients were operated on. Complications encountered were one case of low-located rectovaginal fistula that was treated conservatively; one case of partial glans necrosis resulting in a scarred but sensitive clitoris; one case of large labia majora requiring reduction; and one case of short vagina requiring surgical revision with autologous cultured oral cells that was successful. All patients had adequate vagina, experienced sexual intercourse, and were satisfied with results. Autologous cultured oral epithelium transplantation is feasible, safe, and advantageous. Satisfactory neovaginas were provided; the procedure is relatively easy to perform and provides a thin, mucosa-lined neovagina with a sufficient amount of secretion.

摘要

已经描述了各种用于男变女易性癖患者的阴道成形术方法,但没有一种是理想的。本文介绍了使用培养的自体口腔上皮覆盖新阴道壁的方法。对 6 名患者进行了手术。遇到的并发症包括一例低位直肠阴道瘘,采用保守治疗;一例部分龟头坏死导致有疤痕但敏感的阴蒂;一例大阴唇需要缩小;一例阴道短,需要用自体培养的口腔细胞进行手术修正,手术成功。所有患者均有足够的阴道,能进行性交,对结果满意。自体培养的口腔上皮移植是可行的、安全的和有利的。提供了满意的新阴道;该手术相对容易进行,并提供了一个薄的、黏膜衬里的新阴道,有足够的分泌物。

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