Isolated limb infusion: technical aspects.

OBJECTIVE

To describe the technique of isolated limb infusion (ILI) for regional high dose chemotherapy in patients with advanced malignancies confined to a limb, as currently practiced at Melanoma Institute Australia (MIA).

BACKGROUND

ILI is progressively being used around the world but to date the reported response rates are generally lower than those reported by MIA.

DISCUSSION

This description of the ILI protocol at MIA provides details that may allow other surgeons to improve results.