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A nuclear deoxyribonucleic acid analysis of normal and abnormal vulvar epithelium.

作者信息

Evans A S, Monaghan J M, Anderson M C

出版信息

Obstet Gynecol. 1987 May;69(5):790-3.

PMID:2437504
Abstract

Vulvar and groin skin from 21 women with clinical squamous cell carcinoma of the vulva was compared with that from nine patients with vulvar intraepithelial neoplasia. Feulgen-stained nuclear densitometry showed a constancy of Feulgen-deoxyribonucleic acid (DNA) density in normal epithelium and all subepithelial connective tissue nuclei. At three sites--tumor edge, opposite labia, and perineum--there were significant differences in nuclear chromatin content between the two groups and also as compared with normal epithelium.

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