Kimmel A S, Magargal L E, Maizel R, Robb-Doyle E
Ophthalmic Surg. 1987 Feb;18(2):126-8.
Of the 256 sickle patients with hemaglobinopathies SC, SS and S-thal referred to the Wills Eye Hospital Retina Vascular Service from 1966 through 1983, 64 (50%) of the 128 males and 71 (55%) of the 128 females were less than 20 years old. Proliferative sickle retinopathy (PSR) was documented by fluorescein angiography in five of the males (8%) and two of the females (3%) under age 20. Included in this series is a 13-year-old black girl with homozygous sickle cell anemia (HbSS), to our knowledge the youngest reported case of PSR in an SS patient. This report emphasizes the importance of ophthalmic examinations in teenage sickle patients to detect and treat proliferative disease.
1966年至1983年间转诊至威尔斯眼科医院视网膜血管科的256例患有血红蛋白病SC、SS和S-地中海贫血的镰状细胞病患者中，128名男性患者中有64名（50%）以及128名女性患者中有71名（55%）年龄小于20岁。20岁以下的男性中有5名（8%）、女性中有2名（3%）经荧光素血管造影证实患有增殖性镰状视网膜病变（PSR）。该系列病例中有一名13岁的纯合子镰状细胞贫血（HbSS）黑人女孩，据我们所知，这是报告中最年轻的SS患者发生PSR的病例。本报告强调了对青少年镰状细胞病患者进行眼科检查以检测和治疗增殖性疾病的重要性。
