Wierzbicka Małgorzata, Popko Mariola, Piskadło Karolina, Czepczyński Rafał, Stankowska Aleksandra, Piętka Tomasz, Dziuk Mirosław, Szyfter Witold
Department of Otolaryngology, Poznan University of Medical Sciences, Poland.
Fifth Year Medical Faculty Student, Poznan University of Medical Sciences, Poland.
Rep Pract Oncol Radiother. 2011 Sep 29;16(5):184-8. doi: 10.1016/j.rpor.2011.04.007. eCollection 2011.
Posttreatment surveillance for the local and regional recurrence of the head and neck squamous cell carcinoma often requires a multimodality techniques that include PET combined with CT, MRI, US.
The purpose of this study is to compare the diagnostic performance of two imaging techniques (PET/CT and US), and their combined use for the detection of a subclinical regional recurrence in patients after HNSCC treatment.
83 patients after completion of the HNSCC treatment underwent both US and PET/CT on the mean follow-up of 14 months after initial treatment.
The sensitivity and specificity of PET/CT were 86% and 82%, respectively; US values reached 81% and 87%, respectively. PPV was 79% for PET/CT, and 83% for US. NPV was 89% for PET/CT, and 85% for US. The overall accuracy for PET/CT and US was 84% for both methods.
US could be regarded as complementary to PET/CT as the procedures with highest sensitivity, specificity and NPV for detecting subclinical regional recurrences after HNSCC treatment.
头颈部鳞状细胞癌局部和区域复发的治疗后监测通常需要多种模式技术，包括PET与CT、MRI、超声联合使用。
本研究的目的是比较两种成像技术（PET/CT和超声）及其联合使用在检测头颈部鳞状细胞癌治疗后患者亚临床区域复发方面的诊断性能。
83名头颈部鳞状细胞癌治疗完成后的患者在初始治疗后平均随访14个月时接受了超声和PET/CT检查。
PET/CT的敏感性和特异性分别为86%和82%；超声的值分别达到81%和87%。PET/CT的阳性预测值为79%，超声为83%。PET/CT的阴性预测值为89%，超声为85%。PET/CT和超声两种方法的总体准确率均为84%。
超声可被视为PET/CT的补充，作为检测头颈部鳞状细胞癌治疗后亚临床区域复发的敏感性、特异性和阴性预测值最高的检查方法。
