早期乳腺癌的部分乳腺照射技术
Partial breast irradiation techniques in early breast cancer.
作者信息
Kacprowska Agata, Jassem Jacek
机构信息
Department of Oncology and Radiotherapy, Medical University of Gdansk, Debinki 7, 80-952 Gdansk, Poland.
出版信息
Rep Pract Oncol Radiother. 2011 Oct 14;16(6):213-20. doi: 10.1016/j.rpor.2011.08.003.
Abstract
Whole breast irradiation represents an integral part of combined breast-conserving treatment of early breast cancer. A new concept includes replacing traditionally fractionated whole breast postoperative radiotherapy by accelerated partial breast irradiation. The latter involves a variety of techniques and may be applied intraoperatively or shortly after the surgery. The intraoperative techniques include photon or electron external beam irradiation and interstitial high dose rate (HDR) brachytherapy, whereas the postoperative techniques comprise interstitial brachytherapy, be it HDR, pulse dose rate (PDR) or low dose rate (LDR), intracavitary brachytherapy and external beam radiotherapy using electrons, photons or protons. This article presents accelerated partial breast irradiation techniques, ongoing phase III trials evaluating their value and recommendations for clinical practice.
摘要
全乳照射是早期乳腺癌保乳综合治疗的一个重要组成部分。一个新的概念是用加速部分乳腺照射取代传统的术后全乳分割放疗。后者涉及多种技术，可在术中或术后不久应用。术中技术包括光子或电子外照射束放疗和组织间高剂量率（HDR）近距离放疗，而术后技术包括组织间近距离放疗，无论是HDR、脉冲剂量率（PDR）还是低剂量率（LDR），腔内近距离放疗以及使用电子、光子或质子的外照射束放疗。本文介绍了加速部分乳腺照射技术、评估其价值的正在进行的III期试验以及对临床实践的建议。
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