Slosarek Krzysztof, Grządziel Aleksandra, Osewski Wojciech, Dolla Lukasz, Bekman Barbara, Petrovic Borislava
Radiotherapy and Brachytherapy Planning Department, Center of Oncology - MSC Memorial Institute, Gliwice Branch, Poland.
Radiotherapy Department, Institute of Oncology Vojvodine, Sremska Kamienica, Serbia.
Rep Pract Oncol Radiother. 2012 Feb 10;17(2):97-103. doi: 10.1016/j.rpor.2012.01.004. eCollection 2012.
To examine the impact of beam rate on dose distribution in IMRT plans and then to evaluate agreement of calculated and measured dose distributions for various beam rate values.
Accelerators used in radiotherapy utilize some beam rate modes which can shorten irradiation time and thus reduce ability of patient movement during a treatment session. This aspect should be considered in high conformal dynamic techniques.
Dose calculation was done for two different beam rates (100 MU/min and 600 MU/min) in an IMRT plan. For both, a comparison of Radiation Planning Index (RPI) and MU was conducted. Secondly, the comparison of optimal fluence maps and corresponding actual fluence maps was done. Next, actual fluence maps were measured and compared with the calculated ones. Gamma index was used for that assessment. Additionally, positions of each leaf of the MLC were controlled by home made software.
Dose distribution obtained for lower beam rates was slightly better than for higher beam rates in terms of target coverage and risk structure protection. Lower numbers of MUs were achieved in 100 MU/min plans than in 600 MU/min plans. Actual fluence maps converted from optimal ones demonstrated more similarity in 100 MU/min plans. Better conformity of the measured maps to the calculated ones was obtained when a lower beam rate was applied. However, these differences were small. No correlation was found between quality of fluence map conversion and leaf motion accuracy.
Execution of dynamic techniques is dependent on beam rate. However, these differences are minor. Analysis shows a slight superiority of a lower beam rate. It does not significantly affect treatment accuracy.
研究射束速率对调强放射治疗(IMRT)计划中剂量分布的影响,然后评估不同射束速率值下计算剂量分布与测量剂量分布的一致性。
放射治疗中使用的加速器采用一些射束速率模式,可缩短照射时间,从而降低治疗过程中患者移动的可能性。在高适形动态技术中应考虑这一方面。
在一个IMRT计划中,针对两种不同的射束速率(100 MU/分钟和600 MU/分钟)进行剂量计算。对两者都进行了放射治疗计划指数(RPI)和MU的比较。其次,进行了最佳通量图与相应实际通量图的比较。接下来,测量实际通量图并与计算得到的通量图进行比较。使用伽马指数进行该评估。此外,多叶准直器(MLC)每片叶片的位置由自制软件控制。
就靶区覆盖和危及器官保护而言,较低射束速率获得的剂量分布略优于较高射束速率。100 MU/分钟计划中的MU数量比600 MU/分钟计划中的少。从最佳通量图转换而来的实际通量图在100 MU/分钟计划中显示出更高的相似性。当应用较低射束速率时,测量图与计算图的一致性更好。然而,这些差异很小。在通量图转换质量与叶片运动精度之间未发现相关性。
动态技术的执行取决于射束速率。然而,这些差异较小。分析表明较低射束速率略具优势。它不会显著影响治疗精度。