Suppr超能文献

使用矩阵求和法进行近距离放射治疗中的三维剂量计算。

Using matrix summation method for three dimensional dose calculation in brachytherapy.

作者信息

Zibandeh-Gorji Mahmoud, Mowlavi Ali Asghar, Mohammadi Saeed

机构信息

Physics Department of Payamnor University of Tehran, Tehran, Iran.

Physics Department of Sabsevar Tarbiat Moallem University, Sabzevar, Iran ; TRIL, ICTP, Trieste, Italy.

出版信息

Rep Pract Oncol Radiother. 2012 Feb 9;17(2):110-4. doi: 10.1016/j.rpor.2012.01.003. eCollection 2012.

Abstract

AIM

The purpose of this study is to calculate radiation dose around a brachytherapy source in a water phantom for different seed locations or rotation the sources by the matrix summation method.

BACKGROUND

Monte Carlo based codes like MCNP are widely used for performing radiation transport calculations and dose evaluation in brachytherapy. But for complicated situations, like using more than one source, moving or rotating the source, the routine Monte Carlo method for dose calculation needs a long time running.

MATERIALS AND METHODS

The MCNPX code has been used to calculate radiation dose around a (192)Ir brachytherapy source and saved in a 3D matrix. Then, we used this matrix to evaluate the absorbed dose in any point due to some sources or a source which shifted or rotated in some places by the matrix summation method.

RESULTS

Three dimensional (3D) dose results and isodose curves were presented for (192)Ir source in a water cube phantom shifted for 10 steps and rotated for 45 and 90° based on the matrix summation method. Also, we applied this method for some arrays of sources.

CONCLUSION

The matrix summation method can be used for 3D dose calculations for any brachytherapy source which has moved or rotated. This simple method is very fast compared to routine Monte Carlo based methods. In addition, it can be applied for dose optimization study.

摘要

目的

本研究的目的是通过矩阵求和法计算水模体中近距离放射治疗源周围不同籽源位置或源旋转时的辐射剂量。

背景

基于蒙特卡罗的代码如MCNP被广泛用于近距离放射治疗中的辐射传输计算和剂量评估。但对于复杂情况,如使用多个源、移动或旋转源,常规的蒙特卡罗剂量计算方法需要很长的运行时间。

材料与方法

使用MCNPX代码计算(192)铱近距离放射治疗源周围的辐射剂量,并保存到一个三维矩阵中。然后,我们使用该矩阵通过矩阵求和法评估由于某些源或在某些位置移动或旋转的源在任意点的吸收剂量。

结果

基于矩阵求和法,给出了(192)铱源在水立方模体中移动10步、旋转45°和90°时的三维剂量结果和等剂量曲线。此外,我们将该方法应用于一些源阵列。

结论

矩阵求和法可用于任何移动或旋转的近距离放射治疗源的三维剂量计算。与常规的基于蒙特卡罗的方法相比,这种简单方法非常快速。此外,它可应用于剂量优化研究。

相似文献

1
Using matrix summation method for three dimensional dose calculation in brachytherapy.
Rep Pract Oncol Radiother. 2012 Feb 9;17(2):110-4. doi: 10.1016/j.rpor.2012.01.003. eCollection 2012.
2
Monte Carlo dose calculation of GZP6 (60)Co stepping source based on a matrix shift technique.
Rep Pract Oncol Radiother. 2010 Dec 21;16(1):10-3. doi: 10.1016/j.rpor.2010.11.005. eCollection 2010.
4
A Monte Carlo study on dose distribution evaluation of Flexisource (192)Ir brachytherapy source.
Rep Pract Oncol Radiother. 2015 May-Jun;20(3):204-9. doi: 10.1016/j.rpor.2015.01.006. Epub 2015 Feb 23.
10
Monte Carlo dosimetry of the IRAsource high dose rate (192)Ir brachytherapy source.
Australas Phys Eng Sci Med. 2016 Jun;39(2):413-22. doi: 10.1007/s13246-016-0429-y. Epub 2016 Feb 23.

本文引用的文献

1
Monte Carlo dose calculation of GZP6 (60)Co stepping source based on a matrix shift technique.
Rep Pract Oncol Radiother. 2010 Dec 21;16(1):10-3. doi: 10.1016/j.rpor.2010.11.005. eCollection 2010.
2
Air kerma strength characterization of a GZP6 Cobalt-60 brachytherapy source.
Rep Pract Oncol Radiother. 2010 Nov 9;15(6):190-4. doi: 10.1016/j.rpor.2010.10.002. eCollection 2010.
3
ACR-SNM Task Force on Nuclear Medicine Training: report of the task force.
J Nucl Med. 2011 Jun;52(6):998-1002. doi: 10.2967/jnumed.111.092171. Epub 2011 May 13.
4
A novel method for accurate needle-tip identification in trans-rectal ultrasound-based high-dose-rate prostate brachytherapy.
Brachytherapy. 2011 Nov-Dec;10(6):466-73. doi: 10.1016/j.brachy.2011.02.214. Epub 2011 May 5.
6
Gold nanorods: multifunctional agents for cancer imaging and therapy.
Methods Mol Biol. 2010;624:119-30. doi: 10.1007/978-1-60761-609-2_8.
7
Partial breast irradiation or whole breast radiotherapy for early breast cancer: a meta-analysis of randomized controlled trials.
Breast J. 2010 May-Jun;16(3):245-51. doi: 10.1111/j.1524-4741.2010.00905.x. Epub 2010 Feb 23.
8
Targeted therapy in radioiodine refractory thyroid cancer.
Q J Nucl Med Mol Imaging. 2009 Oct;53(5):520-5.
9
A new method of anatomically conformal vaginal cuff HDR brachytherapy.
Gynecol Oncol. 2010 Mar;116(3):413-8. doi: 10.1016/j.ygyno.2009.10.044. Epub 2009 Nov 4.
10

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验