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铱源高剂量率(192)Ir近距离治疗源的蒙特卡罗剂量测定法

Monte Carlo dosimetry of the IRAsource high dose rate (192)Ir brachytherapy source.

作者信息

Sarabiasl Akbar, Ayoobian Navid, Jabbari Iraj, Poorbaygi Hossein, Javanshir Mohammad Reza

机构信息

Department of Nuclear Engineering, Faculty of Advanced Science & Technologies, University of Isfahan, Postal Code: 81756-73441, Isfahan, Iran.

Nuclear Science Research School, Nuclear Science and Technology Research Institute NSTRI, Tehran, Iran.

出版信息

Australas Phys Eng Sci Med. 2016 Jun;39(2):413-22. doi: 10.1007/s13246-016-0429-y. Epub 2016 Feb 23.

Abstract

High-dose-rate (HDR) brachytherapy is a common method for cancer treatment in clinical brachytherapy. Because of the different source designs, there is a need for specific dosimetry data set for each HDR model. The purpose of this study is to obtain detailed dose rate distributions in water phantom for a first prototype HDR (192)Ir brachytherapy source model, IRAsource, and compare with the other published works. In this study, Monte Carlo N-particle (MCNP version 4C) code was used to simulate the dose rate distributions around the HDR source. A full set of dosimetry parameters reported by the American Association of Physicists in Medicine Task Group No. 43U1 was evaluated. Also, the absorbed dose rate distributions in water, were obtained in an along-away look-up table. The dose rate constant, Λ, of the IRAsource was evaluated to be equal to 1.112 ± 0.005 cGy h(-1) U(-1). The results of dosimetry parameters are presented in tabulated and graphical formats and compared with those reported from other commercially available HDR (192)Ir sources, which are in good agreement. This justifies the use of specific data sets for this new source. The results obtained in this study can be used as input data in the conventional treatment planning systems.

摘要

高剂量率(HDR)近距离放射治疗是临床近距离放射治疗中一种常见的癌症治疗方法。由于源设计不同,每种HDR模型都需要特定的剂量测定数据集。本研究的目的是获取首个原型HDR(192)铱近距离放射治疗源模型IRAsource在水模体中的详细剂量率分布,并与其他已发表的研究进行比较。在本研究中,使用蒙特卡罗N粒子(MCNP版本4C)代码来模拟HDR源周围的剂量率分布。对美国医学物理学家协会第43U1任务组报告的全套剂量测定参数进行了评估。此外,还通过沿远离方向的查找表获得了水中的吸收剂量率分布。IRAsource的剂量率常数Λ经评估等于1.112±0.005 cGy h(-1)U(-1)。剂量测定参数的结果以表格和图形形式呈现,并与其他市售HDR(192)铱源报告的结果进行比较,结果吻合良好。这证明了针对这种新源使用特定数据集的合理性。本研究获得的结果可作为传统治疗计划系统的输入数据。

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