Soares André, Louro Luís Vasco, Almeida Marta, Sousa Olga
Radiotherapy Department, Instituto Português de Oncologia do Porto Francisco Gentil, E.P.E, Portugal.
Oncology Department, Hospital Escala, Braga, Portugal.
Rep Pract Oncol Radiother. 2012 Jul 15;17(6):384-8. doi: 10.1016/j.rpor.2012.05.004. eCollection 2012.
Thymomas are rare neoplasms that have an indolent growth with a preferentially intra-thoracic dissemination pattern. Surgery is currently the standard treatment of thymomas; however radiotherapy is often used in an adjuvant setting due to a high sensitivity of these tumors to such treatment. Postoperative entire hemithoracic irradiation has been used in selected Masaoka stage IVa cases after complete surgical excision of metastatic lesions. In the present article, the authors report three cases of Masaoka stage IVa thymoma that underwent entire hemithorax irradiation after surgical excision of metastatic lesions. The first two patients presented as stage IVa thymomas. The third case consisted of a pleural recurrence of a thymoma. Hemithoracic irradiation with low doses has been used by different authors; the available data shows that it is a well-tolerated treatment that could potentially lead to better loco-regional control and increased overall survival.
胸腺瘤是一种罕见的肿瘤，生长缓慢，优先表现为胸内播散模式。手术是目前胸腺瘤的标准治疗方法；然而，由于这些肿瘤对放疗高度敏感，放疗常被用作辅助治疗。对于部分Masaoka IVa期病例，在完整切除转移灶后，术后会进行全半胸照射。在本文中，作者报告了3例Masaoka IVa期胸腺瘤病例，这些病例在手术切除转移灶后接受了全半胸照射。前两名患者表现为IVa期胸腺瘤。第三例是胸腺瘤胸膜复发。不同作者使用了低剂量的半胸照射；现有数据表明，这是一种耐受性良好的治疗方法，可能会带来更好的局部区域控制并提高总生存率。
