Heffes Nahmod L A, Litwin N, Guastavino E, Licastro R
Acta Gastroenterol Latinoam. 1986;16(1):47-51.
24 children whose ages ranged from 10 days to 14 years (x 5.5. ys.), 16 males and 8 females, hospitalized in our Service on account of extra-digestive were studied. Creatinine and amylase determination were performed on serum and 24 hs. urine specimens; lipase activity was measured only in serum. Amylase-creatinine clearance ratio varied between 1.3 and 5.8% (x 3.1 +/- 1.3). Serum amylase ranged from 36 to 460 U/l (x 123 U/l). Five patients had hyperamylasemia. 2 were urlian parotiditis, 2 were under clinical surveillance after surgery and the last one was a septic meningitis. All of them showed amylase-creatinine ratio values up to 2.5%. Serum lipase ranged from 6 to 197 U/l (x 79 U/l), falling into the normal interval. No abnormal clearance was found.
hyperamylasemia is not specific for pancreatic disturbances in children; the serum lipase and the amylase-creatinine clearance ratio seem to be useful tools to rule out pancreatic involvement in hyperamylasemic patients.
研究了24名年龄在10天至14岁（平均5.5岁）之间的儿童，其中16名男性，8名女性，因消化系统外疾病入住我院。对血清和24小时尿液标本进行肌酐和淀粉酶测定；仅在血清中测量脂肪酶活性。淀粉酶-肌酐清除率在1.3%至5.8%之间变化（平均3.1%±1.3%）。血清淀粉酶范围为36至460 U/l（平均123 U/l）。5例患者有高淀粉酶血症。2例为流行性腮腺炎，2例术后接受临床监测，最后1例为化脓性脑膜炎。所有患者的淀粉酶-肌酐比值均高达2.5%。血清脂肪酶范围为6至197 U/l（平均79 U/l），处于正常区间。未发现异常清除情况。
高淀粉酶血症在儿童中并非胰腺疾病所特有；血清脂肪酶和淀粉酶-肌酐清除率似乎是排除高淀粉酶血症患者胰腺受累的有用工具。
