Krajcírová M, Cernák A, Kasanická A, Behulová D, Cierna I
II. detská klinika DFNsP, Bratislava.
Cesk Pediatr. 1993 Nov;48(11):648-50.
Elevated alpha-amylase activity in serum was thought for a long time to be a laboratory standard in diagnosis of acute pancreatic disease. The purpose of this study was to evaluate the clinical usefulness of routine measurement of total serum amylase (using the Boehringer Mannheim EPS method) and pancreatic isoamylase (using Boehringer Mannheim EPS method) and lipase (Kodak Eastman) in children. Authors examined the group of 93 children with abdominal pain whose age ranged from 5 to 17 years. In previous laboratory measurements using Spofa test (Slovakofarma) they were found to have elevated alpha-amylase in serum, thus the pancreatic disorder was put in question. A pancreatic disorder was proven in 9 children (9.7%) from this group. The authors consider the measurements given above to be the markers significantly improving the specificity of routine biochemistry in children with pancreatic diseases.
长期以来，血清中α-淀粉酶活性升高一直被视为诊断急性胰腺疾病的实验室标准。本研究的目的是评估常规检测儿童血清总淀粉酶（采用勃林格殷格翰EPS法）、胰腺同工淀粉酶（采用勃林格殷格翰EPS法）和脂肪酶（柯达伊士曼法）的临床实用性。作者检查了93名年龄在5至17岁之间、有腹痛症状的儿童。在之前使用斯洛伐克法玛公司（Spofa）的检测中，发现他们血清中的α-淀粉酶升高，因此怀疑患有胰腺疾病。该组中有9名儿童（9.7%）被证实患有胰腺疾病。作者认为上述检测是显著提高胰腺疾病患儿常规生物化学检测特异性的标志物。
