WPI-Advanced Institute for Materials Research (WPI-AIMR), Tohoku University , Sendai 980-8577, Japan.
Org Lett. 2014 Jan 17;16(2):620-3. doi: 10.1021/ol403573r. Epub 2013 Dec 30.
A novel and highly efficient Cu-catalyzed C-H amination of the monofunctionalized hydrofullerenes for the synthesis of 1,4-difunctional fullerenes has been reported. A new series of 1,4-fullerene derivatives having various monoamine addends were synthesized in good to high yields under mild reaction conditions. The controlled experiments revealed that the reaction proceeds through the formation of a fullerene monoradical as a key intermediate followed by coupling with an amine radical.
报道了一种新型、高效的铜催化单官能化富勒烯 C-H 胺化反应，用于合成 1,4-二官能化富勒烯。在温和的反应条件下，以良好至高产率合成了一系列具有各种单胺取代基的新型 1,4-富勒烯衍生物。控制实验表明，反应通过形成富勒烯单自由基作为关键中间体，然后与胺自由基偶联进行。
