Shear M K, Kligfield P, Harshfield G, Devereux R B, Polan J J, Mann J J, Pickering T, Frances A J
Am J Psychiatry. 1987 May;144(5):633-7. doi: 10.1176/ajp.144.5.633.
This study assessed cardiac rate and rhythm by ambulatory monitoring in 23 patients with panic disorder or agoraphobia with panic attacks. The patients had a higher than normal mean daily density of ventricular premature complexes (VPCs), but complex ventricular arrhythmias were uncommon. Heart rate was greater during panic intervals than during asymptomatic periods. The prevalence of arrhythmias within symptomatic intervals was similar during panic, partial panic, and anxiety and was significantly higher than during asymptomatic intervals. However, most panic episodes had no arrhythmias, and arrhythmias during panic intervals were simple VPCs.
本研究通过动态监测评估了23例惊恐障碍或伴有惊恐发作的广场恐惧症患者的心率和心律。这些患者的室性早搏复合体（VPC）平均每日密度高于正常水平，但复杂性室性心律失常并不常见。惊恐发作期间的心率高于无症状期。在惊恐发作、部分惊恐发作和焦虑期间，有症状发作间期心律失常的患病率相似，且显著高于无症状发作间期。然而，大多数惊恐发作并无心律失常，惊恐发作间期的心律失常为单纯的室性早搏。
