Işk Sakine, Arkan-Ayyldz Zeynep, Sozmen Sule Caglayan, Karaman Özkan, Uzuner Nevin
From the Department of Pediatric Allergy, Dokuz Eylul University Hospital, Izmir, Turkey.
Pediatr Emerg Care. 2014 Jan;30(1):38-9. doi: 10.1097/PEC.0000000000000036.
Cold urticaria (CU) is a subtype of physical urticaria characterized by the development of urticaria and angioedema after cold exposure. Symptoms typically occur minutes after skin exposure to cold air, liquids, and objects. Most common method to confirm the diagnosis of CU is through ice cube challenge test, but 20% of patients with CU have negative ice cube challenge test results. The greatest risk with this kind of urticaria is the development of systemic reaction resulting in a hemodynamic collapse during generalized cold exposure. We report a case of a patient who developed CU and anaphylaxis during swimming and diving in the sea.
寒冷性荨麻疹（CU）是物理性荨麻疹的一种亚型，其特征为在接触寒冷后出现荨麻疹和血管性水肿。症状通常在皮肤暴露于冷空气、液体和物体后几分钟出现。确诊CU最常用的方法是冰块激发试验，但20%的CU患者冰块激发试验结果为阴性。这种荨麻疹最大的风险是在全身暴露于寒冷时发生全身反应，导致血流动力学崩溃。我们报告一例患者在海中游泳和潜水时发生CU和过敏反应的病例。
