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单克隆抗体可确定牛白血病病毒(BLV)主要内部蛋白p24上的抗原区域。

Monoclonal antibodies define antigenic regions on the major internal protein p24 of bovine leukemia virus (BLV).

作者信息

Aida Y, Onuma M, Tsukiyama K, Ogawa Y, Fujieda T, Mikami T, Izawa H

出版信息

Arch Virol. 1987;94(3-4):315-21. doi: 10.1007/BF01310725.

Abstract

The major core protein p24 of bovine leukemia virus (BLV) was characterized by ten monoclonal antibodies. Competitive binding assays were performed in order to analyze the topography of the antigenic determinants by enzyme-linked immunosorbent assay. At least three independent antigenic regions were demonstrated on the BLV p24 molecule.

摘要

牛白血病病毒(BLV)的主要核心蛋白p24由十种单克隆抗体进行了表征。通过酶联免疫吸附测定进行竞争结合试验,以分析抗原决定簇的拓扑结构。在BLV p24分子上至少证实了三个独立的抗原区域。

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