Yan Zhongyu, Wang Yongzhe, Zhang Zhengyu
From the Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
J Comput Assist Tomogr. 2014 Jan-Feb;38(1):14-9. doi: 10.1097/RCT.0b013e3182a7764c.
Inflammatory myofibroblastic tumor (IMT) is chronic inflammatory lesions of unknown origins. The preoperative diagnosis for tumors in the sinonasal cavity is difficult to distinguish between IMT and aggressive malignancy in most cases. The purpose of this study was to evaluate the imaging features of IMT distinguishing the 2 types of tumors.
Computed tomography and magnetic resonance imaging were identified retrospectively with IMT in 14 cases and with aggressive malignancy in 38 cases in the sinonasal cavity proven by pathology. Imaging findings were evaluated, including the configuration, extent, margin, calcification, bone involvement, T1WI and T2WI signal intensity, and degree of enhancement.
There was a significant difference between IMT and aggressive malignancy regarding the configuration, extension, calcification, bone change, signal intensity and homogeneous on T2-weighted imaging, and degree of enhancement (P < 0.05).
Inflammatory myofibroblastic tumor and aggressive malignancy have some different imaging features that could be helpful in the differentiation between the lesions. Bone erosion with sclerosis, calcification when present, typically homogenous and never hyperintense of T2 appearance, and mild enhancement played an important role in differentiating sinonasal IMT from malignancies.
炎性肌纤维母细胞瘤（IMT）是起源不明的慢性炎性病变。在大多数情况下，鼻窦腔肿瘤的术前诊断很难区分IMT和侵袭性恶性肿瘤。本研究的目的是评估IMT的影像学特征以区分这两种类型的肿瘤。
回顾性分析经病理证实的14例鼻窦腔IMT和38例鼻窦腔侵袭性恶性肿瘤的计算机断层扫描和磁共振成像。评估影像学表现，包括形态、范围、边界、钙化、骨质受累情况、T1加权像和T2加权像信号强度以及强化程度。
IMT和侵袭性恶性肿瘤在形态、范围、钙化、骨质改变、T2加权成像上的信号强度和均匀性以及强化程度方面存在显著差异（P < 0.05）。
炎性肌纤维母细胞瘤和侵袭性恶性肿瘤具有一些不同的影像学特征，这有助于区分病变。骨质侵蚀伴硬化、存在钙化时、T2表现通常均匀且从不呈高信号以及轻度强化在区分鼻窦腔IMT和恶性肿瘤中起重要作用。
