Phillips C D, Futterer S F, Lipper M H, Levine P A
Department of Radiology, University of Virginia Health Sciences Center, Charlottesville 22908, USA.
Radiology. 1997 Feb;202(2):477-80. doi: 10.1148/radiology.202.2.9015077.
To determine the computed tomographic (CT) and magnetic resonance (MR) imaging appearance of sinonasal undifferentiated carcinoma.
Findings from 11 patients with histopathologically proved sinonasal undifferentiated carcinoma were retrospectively reviewed. All 11 patients had undergone CT, and six of them had undergone MR imaging.
The tumors usually were large (larger than 4 cm in maximum dimension in eight patients), had poorly defined margins, and arose within the ethmoid sinuses and superior nasal cavity. The aggressive nature of the tumor was demonstrated by bone destruction (n = 10) and by invasion of adjacent structures, including paranasal sinuses (n = 10), anterior fossa (n = 7), orbits (n = 4), pterygopalatine fossa (n = 2), parapharyngeal space (n = 1), and cavernous sinus (n = 1). On contrast material-enhanced CT scans, all tumors were enhanced to varying degrees. They tended to be noncalcified (n = 10) and often caused sinus obstruction (n = 10). MR signal intensity of the lesions was isointense to muscle on T1-weighted images in all six patients and iso- to hyperintense on T2-weighted images in five patients. Heterogeneous enhancement of tumors was seen on gadolinium-enhanced images.
Sinonasal undifferentiated carcinoma cannot be distinguished from other tumors of this region (with the possible exception of melanoma) on the basis of imaging features.
确定鼻窦未分化癌的计算机断层扫描（CT）和磁共振成像（MR）表现。
回顾性分析11例经组织病理学证实的鼻窦未分化癌患者的检查结果。所有11例患者均接受了CT检查，其中6例还接受了MR成像检查。
肿瘤通常较大（8例患者最大径大于4 cm），边界不清，起源于筛窦和鼻腔上部。骨破坏（n = 10）及侵犯相邻结构，包括鼻窦（n = 10）、前颅窝（n = 7）、眼眶（n = 4）、翼腭窝（n = 2）、咽旁间隙（n = 1）和海绵窦（n = 1），显示出肿瘤的侵袭性。在对比剂增强CT扫描上，所有肿瘤均有不同程度强化。它们往往无钙化（n = 10），常导致鼻窦阻塞（n = 10）。6例患者病变在T1加权像上的信号强度与肌肉等信号，5例患者在T2加权像上呈等至高信号。钆增强图像上可见肿瘤不均匀强化。
基于影像学特征，鼻窦未分化癌无法与该区域的其他肿瘤（黑色素瘤可能除外）相鉴别。
