Soós Zsuzsanna, Salamon Mónika, Oláh Roland, Czégeni Anna, Salamon Ferenc, Folyovich András, Winkler Gábor
Szent János Kórház II. Belgyógyászat-Diabetológia Budapest Diós árok 1-3. 1125.
Szent János Kórház Neurológia Budapest.
Orv Hetil. 2014 Jan 5;155(1):30-3. doi: 10.1556/OH.2014.29800.
Wernicke encephalopathy (or Wernicke-Korsakoff encephalopathy) is a rarely diagnosed neurological disorder, which is caused by vitamin B1 deficiency. In the classical form it is characterized by a typical triad (confusion, oculomotor disturbance and ataxia), however, in the majority of the cases only confusion is present. It can be frequently observed in subjects with chronic alcohol consumption, but it may accompany different pathological states of which end stage malignant diseases are the most importants, where confusion may have different backgrounds. The authors present the case of an old male patient with advanced gastric cancer recognised and treated vitamin B1 deficiency, and they draw attention to difficulties of the diagnosis of Wernicke's disease.
韦尼克脑病(或韦尼克-科尔萨科夫脑病)是一种罕见的神经系统疾病,由维生素B1缺乏引起。典型形式表现为典型三联征(意识模糊、动眼神经功能障碍和共济失调),然而,大多数病例仅出现意识模糊。在慢性饮酒者中较为常见,但也可能伴随不同的病理状态,其中终末期恶性疾病最为重要,意识模糊可能有不同的背景。作者介绍了一例老年男性晚期胃癌患者维生素B1缺乏的诊断和治疗情况,并提请注意韦尼克病诊断的困难。