甲状腺毒症相关性韦尼克脑病
Thyrotoxicosis associated Wernicke's encephalopathy.
作者信息
Bonucchi James, Hassan Ihab, Policeni Bruno, Kaboli Peter
机构信息
Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
出版信息
J Gen Intern Med. 2008 Jan;23(1):106-9. doi: 10.1007/s11606-007-0438-3. Epub 2007 Nov 17.
Abstract
BACKGROUND
Wernicke's encephalopathy is a rare disorder resulting from nutrition deficiency in thiamine (vitamin B1). It is most often associated with chronic alcohol abuse. It can accompany other disorders such as hyperemesis gravidarum and hyperthyroidism.
CASE
We present a case of severe Wernicke's encephalopathy that developed in a male non-alcoholic inpatient that was precipitated by poor nutritional intake and development of thyrotoxicosis. It is likely that the hypermetabolic state from thyrotoxicosis contributed to the development of Wernicke's encephalopathy, which was extremely debilitating.
CONCLUSION
Wernicke's encephalopathy is a severe, life-threatening illness that can be a consequence of hyperthyroidism in addition to alcohol abuse and can be easily prevented with appropriate supplementation of thiamine.
摘要
背景
韦尼克脑病是一种因硫胺素（维生素B1）营养缺乏导致的罕见疾病。它最常与慢性酒精滥用相关。它可伴发其他疾病，如妊娠剧吐和甲状腺功能亢进。
病例
我们报告一例严重韦尼克脑病，该病例发生在一名非酒精性男性住院患者身上，由营养摄入不足和甲状腺毒症引发。甲状腺毒症导致的高代谢状态可能促使了韦尼克脑病的发生，这一疾病极其使人衰弱。
结论
韦尼克脑病是一种严重的、危及生命的疾病，除酒精滥用外，甲状腺功能亢进也可能导致该病，适当补充硫胺素可轻松预防该病。
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