中国 Barrett 食管的荟萃分析。
Meta-analysis of Barrett's esophagus in China.
机构信息
Ying Dong, Xiao-Ying Feng, Chun-Meng Jiang, Department of Gastroenterology, the Second Affiliated Hospital of Dalian Medical University, Dalian 116023, Liaoning Province, China.
出版信息
World J Gastroenterol. 2013 Dec 14;19(46):8770-9. doi: 10.3748/wjg.v19.i46.8770.
AIM
To investigate the epidemiology and characteristics of Barrett's esophagus (BE) in China and compare with cases in the west.
METHODS
Studies were retrieved from the China National Knowledge Infrastructure and PubMed databases using the terms "Barrett" and "Barrett AND China", respectively, as well as published studies about BE in China from 2000 to 2011. The researchers reviewed the titles and abstracts of all search results to determine whether or not the literature was relevant to the current topic of this research. The references listed in the studies were also searched. Inclusion and exclusion criteria for the literature were appropriately established, and the data reported in the selected studies were analyzed. Finally, a meta-analysis was performed.
RESULTS
The current research included 3873 cases of BE from 69 studies. The endoscopic detection rate of BE in China was 1%. The ratio of male to female cases was 1.781 to 1, and the average age of BE patients was 49.07 ± 5.09 years. Island-type and short-segment BE were the most common endoscopic manifestations, accounting for 4.48% and 80.3%, respectively, of all cases studied. Cardiac-type BE was observed in 40.0% of the cases, representing the most common histological characteristic of the condition. Cancer incidence was 1.418 per 1000 person-years.
CONCLUSION
Average age of BE patients in China is lower than in Western countries. Endoscopic detection and cancer incidence were also lower in China.
目的
研究中国 Barrett 食管（BE）的流行病学和特征，并与西方病例进行比较。
方法
在中国国家知识基础设施和 PubMed 数据库中分别使用“Barrett”和“Barrett AND China”作为检索词进行检索，并检索了 2000 年至 2011 年发表的中国 BE 相关研究。研究人员对所有检索结果的标题和摘要进行了审查，以确定文献是否与当前研究主题相关。还对研究中列出的参考文献进行了检索。适当制定了文献的纳入和排除标准，并对选定研究中报告的数据进行了分析。最后进行了荟萃分析。
结果
目前的研究包括 69 项研究中的 3873 例 BE 病例。中国 BE 的内镜检出率为 1%。男女病例比例为 1.781:1，BE 患者的平均年龄为 49.07 ± 5.09 岁。岛型和短段型 BE 是最常见的内镜表现，分别占所有研究病例的 4.48%和 80.3%。40.0%的病例观察到贲门型 BE，是该疾病最常见的组织学特征。癌症发病率为每 1000 人年 1.418 例。
结论
中国 BE 患者的平均年龄低于西方国家。中国的内镜检出率和癌症发病率也较低。
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