Ma X-Q, Cao Y, Wang R, Yan X, Zhao Y, Zou D, Wallander M-A, Johansson S, Liu W, Gu Z, Zhao J, He J
Department of Health Statistics, Second Military Medical University, Shanghai, China.
Dis Esophagus. 2009;22(4):317-22. doi: 10.1111/j.1442-2050.2008.00904.x. Epub 2008 Dec 22.
The prevalence of gastroesophageal reflux disease (GERD) in China is lower than that in the Western countries, but appears to be increasing. The aim of this pilot study was to evaluate the prevalence of GERD in Shanghai, China, and to explore which population characteristics where associated with GERD. A sample of 1200 adult inhabitants of Shanghai, selected using randomized, stratified, multi-stage sampling, completed Mandarin translations of the Reflux Disease Questionnaire and GERD Impact Scale. Potential risk factors for GERD were examined by nested case-control analysis, using Cochran-Armitage trend testing and logistic regression analysis. The response rate was 86.2%; 919 responses were suitable for analysis. The prevalence of GERD, defined as heartburn and/or regurgitation of any frequency during the previous week, was 6.2% in Shanghai. Obesity and urban dwelling were associated with GERD (odds ratio 3.4, 95% confidence interval 1.3-9.3; and odds ratio 3.6, 95% confidence interval 1.2-10.4, respectively). The prevalence of GERD in Shanghai agreed with previous Chinese studies. GERD in Shanghai was associated with obesity and residency in an urban environment.
中国胃食管反流病（GERD）的患病率低于西方国家，但似乎呈上升趋势。这项初步研究的目的是评估中国上海GERD的患病率，并探讨哪些人口统计学特征与GERD相关。采用随机、分层、多阶段抽样方法选取了1200名上海成年居民作为样本，他们完成了反流病问卷和GERD影响量表的中文翻译。通过巢式病例对照分析、 Cochr an - Armitage趋势检验和逻辑回归分析来研究GERD的潜在危险因素。应答率为86.2%；919份应答适合进行分析。在上海，将前一周内有任何频率的烧心和/或反流定义为GERD，其患病率为6.2%。肥胖和居住在城市与GERD相关（优势比分别为3.4，95%置信区间1.3 - 9.3；以及优势比3.6，95%置信区间1.2 - 10.4）。上海GERD的患病率与之前的中国研究结果一致。上海的GERD与肥胖和居住在城市环境有关。
