Kosterin S A, Bratkova N F, Kurskiĭ M D
Biofizika. 1987 Mar-Apr;32(2):327-32.
Kinetics of Ca2+ energy-dependent transport in sarcolemma and mitochondrion fractions of myometrium was studied. On the basis of the results obtained the mechanism of calcium control of smooth muscle relaxation was analysed. In terms of this mechanism kinetic curves of myometrium relaxation were calculated. It follows from their pattern that the mitochondria play the role of the main intercellular depo of Ca2+, while the calcium pump of the sarcolemma carries out fine regulation of this process making its contribution to relaxation at its later stage.
研究了子宫肌层肌膜和线粒体部分中Ca2+能量依赖转运的动力学。根据所得结果，分析了平滑肌舒张的钙控制机制。依据该机制计算了子宫肌层舒张的动力学曲线。从其模式可以看出，线粒体起着细胞间主要Ca2+储存库的作用，而肌膜的钙泵对这一过程进行精细调节，在舒张后期发挥作用。
