一名患有遗传性C2补体缺乏症婴儿的疫苗接种后肾小球肾炎：病例研究
Post-vaccine glomerulonephritis in an infant with hereditary C2 complement deficiency: case study.
作者信息
Kersnik Levart Tanja
机构信息
Tanja Kersnik Levart, Department of Pediatric Nephrology, University Medical Centre, Bohoriceva 20, 1000 Ljubljana, Slovenia,
出版信息
Croat Med J. 2013 Dec;54(6):569-73. doi: 10.3325/cmj.2013.54.569.
Abstract
We describe a case of a post vaccine immune complex-mediated glomerulonephritis in an infant with compound heterozygous mutations of C2 complement component gene, which is the first such case in the literature. The three and a half months old boy presented with clinical and laboratory signs of nephritic syndrome and was successfully treated with methylprednisolone. An explanation of such a clinical picture may lie in the interaction between C2 deficiency and vaccination.
摘要
我们描述了一例患有C2补体成分基因复合杂合突变的婴儿发生疫苗后免疫复合物介导的肾小球肾炎的病例，这是文献中首例此类病例。这名三个月大的男婴出现了肾病综合征的临床和实验室体征，并成功接受了甲泼尼龙治疗。这种临床症状的一种解释可能在于C2缺乏与疫苗接种之间的相互作用。
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