Committee for Quality Assurance, Swiss Society of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, University Hospital Inselspital, Effingerstrasse 102, 3010, Bern, Switzerland.
Arch Gynecol Obstet. 2014 Apr;289(4):903-9. doi: 10.1007/s00404-013-3137-9. Epub 2014 Jan 3.
Tocolysis is an important treatment in the improvement of outcome in preterm labor and preterm birth, provided that its use follows clear evidence-based recommendations. In this expert opinion, the most recent evidence about efficacy and side effects of different tocolytics is being reviewed and evidence-based recommendation about diagnosis and treatment of preterm labor is given. Further aspects such as progesterone administration or antibiotic treatment for the prevention of preterm birth are included. Our review demonstrates that an individualized choice of different tocolytics and additional treatments is necessary to improve short- and long-term neonatal outcome in preterm labor and preterm birth.
保胎治疗是改善早产和早产分娩结局的重要手段，但前提是保胎治疗要遵循明确的循证医学推荐。在本专家意见中，我们对不同保胎药物的最新疗效和副作用证据进行了综述，并就早产的诊断和治疗给出了循证医学推荐。此外，我们还纳入了孕激素治疗或抗生素预防早产等其他方面的内容。我们的综述表明，需要个体化选择不同的保胎药物和其他治疗方法，以改善早产和早产分娩的短期和长期新生儿结局。
