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[一种肠道抗原的免疫组织学研究]

[Immunohistological study of an intestinal antigen].

作者信息

Pugachev K K, Avdeev G I

出版信息

Vopr Onkol. 1987;33(4):41-5.

PMID:2438846
Abstract

The localization of an intestinal antigen in different normal and malignant tissues was studied by indirect immunoperoxidase technique. It was shown that this antigen is characteristic for the cells of the intestinal epithelium. The antigen was revealed in 94.3% of primary and metastatic colonic tumors, 50% of gastric tumors and in all samples of the enterolysed gastric mucosa. The intestinal antigen was not found in colonic carcinoids or in the overwhelming majority of tumors of different origins.

摘要

采用间接免疫过氧化物酶技术研究了一种肠道抗原在不同正常组织和恶性组织中的定位。结果表明,这种抗原是肠道上皮细胞所特有的。在94.3%的原发性和转移性结肠肿瘤、50%的胃肿瘤以及所有肠化生胃黏膜样本中均发现了该抗原。在结肠类癌或绝大多数不同起源的肿瘤中未发现肠道抗原。

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