癫痫迷走神经刺激术的翻修手术：结果和疗效。
Lead revision surgery for vagus nerve stimulation in epilepsy: outcomes and efficacy.
机构信息
Department of Neurosurgery and Brain Repair, Morsani College of Medicine, University of South Florida, 2 Tampa General Circle, USF Health, 7th Floor, Tampa, FL 33606, USA.
Department of Neurology, Morsani College of Medicine, University of South Florida, 2 Tampa General Circle, USF Health, 6th Floor, Tampa, FL 33606, USA.
出版信息
Epilepsy Behav. 2014 Feb;31:110-3. doi: 10.1016/j.yebeh.2013.12.002. Epub 2014 Jan 3.
We present, to our knowledge, the first published analysis of vagus nerve stimulation (VNS) lead revisions to incorporate quality of life, clinical response, and antiepileptic drug (AED) burden in postrevision clinical outcomes. Ten patients were followed and had no postoperative complications. Seven patients had improvement in quality of life, and three experienced no change. Eight patients noted a restoration of clinical response comparable with initial VNS implantation. Seven patients reported 30-60% improvement in seizure reduction, two experienced >60%, and one noted <30%. Six patients had no change in AED burden. Vagus nerve stimulation lead revision should be considered a safe option for patients with VNS lead failure and medically intractable epilepsy.
我们呈现了，据我们所知，第一篇发表的分析迷走神经刺激（VNS）导联修订版，以纳入生活质量、临床反应和抗癫痫药物（AED）负担在修订后的临床结果中。10 名患者得到了随访，没有发生术后并发症。7 名患者的生活质量得到改善，3 名患者没有变化。8 名患者注意到临床反应的恢复与初始 VNS 植入相当。7 名患者报告说癫痫发作减少了 30-60%，2 名患者减少了 >60%，1 名患者减少了 <30%。6 名患者的 AED 负担没有变化。对于 VNS 导联故障和药物难治性癫痫患者，VNS 导联修订应被视为一种安全的选择。
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