Department of Chemistry, The University of Western Ontario, 1151 Richmond Street, London, Ontario, Canada N6A 5B7.
Chem Commun (Camb). 2014 Feb 18;50(14):1668-70. doi: 10.1039/c3cc47775d. Epub 2014 Jan 6.
The Yb(OTf)3 catalyzed [4+2] cycloaddition between donor-acceptor cyclobutanes and nitrosoarenes is disclosed. This method facilitates the synthesis of tetrahydro-1,2-oxazines in good to excellent yields as single diastereomers. Except for a few electron-deficient nitrosoarenes, excellent regioselectivity was observed throughout these studies.
三氟化钇（Yb(OTf)3）催化给体-受体环丁烷和亚硝基芳烃之间的[4+2]环加成反应。该方法有利于以良好至优异的收率作为单一非对映异构体合成四氢-1,2-恶嗪。在这些研究中，除了少数缺电子的亚硝基芳烃外，观察到了极好的区域选择性。
