中间型β地中海贫血患者的脊柱硬膜外髓外造血
Spinal epidural extramedullary haematopoiesis in β-thalassaemia intermedia.
作者信息
Wong Kin Hoi, Li Allen, Lui Tun Hing, Sit Yan Kit
机构信息
Department of Radiology, North District Hospital, Hong Kong, Hong Kong.
出版信息
BMJ Case Rep. 2014 Jan 3;2014:bcr2013201534. doi: 10.1136/bcr-2013-201534.
Abstract
A 22-year-old man known to have β-thalassaemia intermedia since childhood presented with bilateral lower limb weakness after spinal anaesthesia for an elective minor operation of his left leg. MRI and CT scans were performed to rule out acute epidural haematoma; coincidental imaging features of marrow hyperplasia and spinal epidural extramedullary haematopoiesis were found. This article will present and discuss the imaging features, differential diagnosis, management and literature review of the rare occurrence of extramedullary haematopoiesis in the spinal epidural space.
摘要
一名自童年起就患有中间型β地中海贫血的22岁男性，在接受左腿择期小手术的脊髓麻醉后出现双侧下肢无力。进行了MRI和CT扫描以排除急性硬膜外血肿；发现了骨髓增生和脊髓硬膜外髓外造血的巧合影像学特征。本文将介绍并讨论脊髓硬膜外间隙罕见的髓外造血的影像学特征、鉴别诊断、管理及文献综述。
相似文献
1
Spinal epidural extramedullary haematopoiesis in β-thalassaemia intermedia.
BMJ Case Rep. 2014 Jan 3;2014:bcr2013201534. doi: 10.1136/bcr-2013-201534.
2
Epidural extramedullary haemopoiesis in thalassaemia.
Australas Radiol. 2002 Jun;46(2):180-2. doi: 10.1046/j.1440-1673.2001.01031.x.
3
Extramedullary haematopoiesis in thalassaemia: results of radiotherapy: a report of three patients.
Clin Oncol (R Coll Radiol). 1996;8(2):120-2. doi: 10.1016/s0936-6555(96)80120-8.
4
MRI findings of extramedullary haemopoiesis.
Eur Radiol. 2001;11(9):1803-6. doi: 10.1007/s003300000802.
5
Spinal cord compression due to epidural extramedullary haematopoiesis in thalassaemia: MRI.
Neuroradiology. 1997 Dec;39(12):870-2. doi: 10.1007/s002340050524.
6
Existence of cord compression in extramedullary hematopoiesis due to beta thalassemia intermedia.
Hematology. 2008 Jun;13(3):183-6. doi: 10.1179/102453308X343347.
7
Progressive spinal cord compression due to epidural extramedullary hematopoiesis in thalassemia intermedia. A case report and literature review.
Neuroradiol J. 2013 Feb;26(1):111-7. doi: 10.1177/197140091302600119. Epub 2013 Jan 19.
8
Imaging features of focal intrahepatic extramedullary haematopoiesis.
Br J Radiol. 1999 Sep;72(861):906-10. doi: 10.1259/bjr.72.861.10645201.
9
Extramedullary haematopoiesis in thalassaemia major causing spinal cord compression.
Australas Radiol. 2007 Apr;51(2):168-71. doi: 10.1111/j.1440-1673.2007.01689.x.
10
Extramedullary haematopoiesis in beta thalassaemia--unusual presentations: case reports.
Pediatr Endocrinol Rev. 2008 Oct;6 Suppl 1:140-3.
引用本文的文献
1
Radiological Features of Extramedullary Hematopoiesis in a Young Male With Beta-Thalassemia: A Case Report.
Cureus. 2024 Jul 6;16(7):e63945. doi: 10.7759/cureus.63945. eCollection 2024 Jul.
2
Unraveling a Rare Case of Epidural Extramedullary Hematopoiesis in a Patient With Transfusion-Dependent Beta Thalassemia Presenting With Spinal Cord Compression.
Cureus. 2024 Mar 17;16(3):e56352. doi: 10.7759/cureus.56352. eCollection 2024 Mar.
本文引用的文献
1
Extra-medullary haematopoiesis: a pictorial review of its typical and atypical locations.
J Med Imaging Radiat Oncol. 2012 Oct;56(5):538-44. doi: 10.1111/j.1754-9485.2012.02397.x. Epub 2012 Jun 25.
2
Clinical and imaging findings in thalassemia patients with extramedullary hematopoiesis.
Clin Imaging. 2012 Sep-Oct;36(5):475-82. doi: 10.1016/j.clinimag.2011.11.019. Epub 2012 Jun 8.
3
MRI appearances of extramedullary haematopoiesis presenting with cauda equina syndrome in sickle cell disease.
Clin Radiol. 2011 Dec;66(12):1219-22. doi: 10.1016/j.crad.2011.07.043. Epub 2011 Sep 14.
4
Extramedullary hematopoiesis presenting as a compressive cord and cerebral lesion in a patient without a significant hematologic disorder: a case report.
J Med Case Rep. 2010 Oct 12;4:319. doi: 10.1186/1752-1947-4-319.
5
Paraspinal extramedullary hematopoiesis in patients with thalassemia intermedia.
Eur Spine J. 2010 Jun;19(6):871-8. doi: 10.1007/s00586-010-1357-2. Epub 2010 Mar 5.
6
Extramedullary haematopoiesis in thalassaemia major causing spinal cord compression.
Australas Radiol. 2007 Apr;51(2):168-71. doi: 10.1111/j.1440-1673.2007.01689.x.
7
Extramedullary haemopoiesis in thalassemia intermedia presenting as paraplegia.
J Clin Neurosci. 2002 Nov;9(6):721-5. doi: 10.1054/jocn.2001.1038.
8
Epidural extramedullary haemopoiesis in thalassaemia.
Australas Radiol. 2002 Jun;46(2):180-2. doi: 10.1046/j.1440-1673.2001.01031.x.
9
MRI features of epidural extramedullary hematopoiesis.
Eur J Radiol. 2000 Jul;35(1):8-11. doi: 10.1016/s0720-048x(99)00122-9.
10
Hydroxyurea therapy in paraparesis and cauda equina syndrome due to extramedullary haematopoiesis in thalassaemia: improvement of clinical and haematological parameters.
Eur J Haematol. 2000 Jun;64(6):426-9. doi: 10.1034/j.1600-0609.2000.9c165.x.
Zotero 插件