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一名患有β地中海贫血的年轻男性的髓外造血的放射学特征:病例报告

Radiological Features of Extramedullary Hematopoiesis in a Young Male With Beta-Thalassemia: A Case Report.

作者信息

Suryadevara Manasa, Mishra Gaurav V, Shetty Neha D, Mishra Komal, Suryadevara Mounika, Sood Anshul, Javvaji Chaitanya Kumar, Yadav Riya

机构信息

Radiodiagnosis, Datta Meghe Institution of Higher Education and Research, Wardha, IND.

Radiodiagnosis, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2024 Jul 6;16(7):e63945. doi: 10.7759/cureus.63945. eCollection 2024 Jul.

Abstract

The formation of the blood elements and their maturation is called hematopoiesis. In adults, this typically takes place in the bone marrow of vertebrae, ribs, and long bones. In contrast, during fetal development, the primary sites of hematopoiesis are the spleen, liver, and the yolk sac. This process of hematopoiesis, when it occurs in sites other than the bone marrow, is called the extramedullary hematopoiesis (EMH). Extramedullary hematopoiesis usually happens in patients with blood disorders like sickle cell disease and thalassemia, where there is failure of hematopoiesis in the primary sites. Here, we present a young male with beta-thalassemia who presented with shortness of breath and palpitations for one month. This manuscript discusses the imaging findings of the EMH in our patient.

摘要

血液成分的形成及其成熟过程称为造血作用。在成年人中,这一过程通常发生在椎骨、肋骨和长骨的骨髓中。相比之下,在胎儿发育期间,造血作用的主要部位是脾脏、肝脏和卵黄囊。当造血过程发生在骨髓以外的部位时,这一过程称为髓外造血(EMH)。髓外造血通常发生在患有镰状细胞病和地中海贫血等血液疾病的患者身上,这些患者的主要造血部位出现造血功能衰竭。在此,我们报告一名患有β地中海贫血的年轻男性,他出现气短和心悸症状达一个月。本手稿讨论了我们这位患者髓外造血的影像学表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3871/11299045/250b5e3812e4/cureus-0016-00000063945-i01.jpg

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