Stegeman D F, Van Oosterom A, Colon E J
Electroencephalogr Clin Neurophysiol. 1987 Aug;67(2):176-87. doi: 10.1016/0013-4694(87)90042-3.
This study validates current hypotheses for the generation of so-called far-field or stationary somatosensory evoked potential (SEP) components. Changes in the volume conductor configuration and changes in the direction of nerve propagation are demonstrated to be capable of generating such components. Results are based on basic aspects of the theory of volume conduction. It is shown that in an essentially restricted volume conductor any disturbance of uniform nerve propagation in a homogeneous extracellular medium will lead to the generation of non-moving field components. A number of illustrative examples are presented in which intermingling of non-moving and propagating potential fields can be observed. These results can be helpful in unravelling complicated wave forms from the nervous system in which both types of potential field can be distinguished. It is shown that realistic changes within the volume conductor can lead to substantial far-field components. This type of volume conductor induced 'virtual generators' or 'secondary sources' is present in the peripheral nervous system and most probably also in the inhomogeneous structures of the brain.
本研究验证了当前关于所谓远场或稳态体感诱发电位（SEP）成分产生的假说。结果表明，容积导体配置的变化以及神经传播方向的变化能够产生此类成分。这些结果基于容积传导理论的基本方面。研究表明，在本质上受限的容积导体中，均匀细胞外介质中神经均匀传播的任何扰动都会导致产生非移动场成分。文中给出了一些示例，从中可以观察到非移动和传播电位场的混合。这些结果有助于解析神经系统中复杂的波形，其中这两种电位场都可被区分。研究表明，容积导体内的实际变化可导致大量远场成分。这种由容积导体诱导的“虚拟发生器”或“次级源”存在于外周神经系统中，很可能也存在于大脑的非均匀结构中。
